Also known as ON, BM-40, basement-membrane protein 40, secreted protein, acidic, cysteine-rich (osteonectin), SPARC, Secreted protein acidic and rich in cysteine, Osteonectin, SPARC protein, human
Osteonectin (ON) also known as secreted protein acidic and rich in cysteine (SPARC) or basement-membrane protein 40 (BM-40) is a protein that in humans is encoded by the SPARC gene.
via PubMed
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Osteonectin (ON) also known as secreted protein acidic and rich in cysteine (SPARC) or basement-membrane protein 40 (BM-40) is a protein that in humans is encoded by the SPARC gene.
Osteonectin is a glycoprotein in the bone that binds calcium. It is secreted by osteoblasts during bone formation, initiating mineralization and promoting mineral crystal formation. Osteonectin also shows affinity for collagen in addition to bone mineral calcium. A correlation between osteonectin over-expression and ampullary cancers and chronic pancreatitis has been found.
Discovered by embedding cosine similarity (sentence-transformers MiniLM, 384-dim).