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mucin 1, cell surface associated
Sign in to saveAlso known as tumor associated epithelial mucin, PUM, polymorphic epithelial mucin, Tumor-associated mucin, tumor-associated epithelial membrane antigen, mucin-1, KL-6
human protein (annotated by UniProtKB/TrEMBL A0A087WTR1)
In the Vinony graph
Within Vinony's link graph, mucin 1, cell surface associated is referenced by 492 other articles, and connects out to mucin, white blood cell and PubMed.
Vinony files it under Clusters of differentiation, Genes on human chromosome 1 and Human proteins.
Its subject is documented across 11 Wikipedia language editions.
Protein · UniProt
Mucin-1
- Gene
- MUC1
- Organism
- Homo sapiens (Human)
- Length
- 1,255 aa
- Molecular mass
- 122,102 Da
- Evidence
- 1: Evidence at protein level
The alpha subunit has cell adhesive properties. Can act both as an adhesion and an anti-adhesion protein. May provide a protective layer on epithelial cells against bacterial and enzyme attack
Swiss-Prot (reviewed) · via UniProt
Research
313 papers- Targeting the cancer glycocalyx in salivary duct carcinoma: tumor-associated mucin 1 (Tn-MUC1) as a novel cell surface marker.The journal of pathology. Clinical research · 2025
- The endometrial cell surface and implantation. Expression of the polymorphic mucin MUC-1 and adhesion molecules during the endometrial cycle.Annals of the New York Academy of Sciences · 1994
- Cell surface-associated mucins in signal transduction.Trends in cell biology · 2006
- Quantification of MUCIN 1, cell surface associated and MUCIN16, cell surface associated proteins in tears and conjunctival epithelial cells collected from postmenopausal women.Molecular vision · 2013
- The cell surface mucin MUC1 limits the severity of influenza A virus infection.Mucosal immunology · 2017
via PubMed
Clinical Trials
3 registered- PHASE1COMPLETEDVaccine Therapy in Treating Patients With Metastatic Breast CancerDana-Farber Cancer Institute · NCT00003761
- PHASE1UNKNOWNClinical Safety and Preliminary Efficacy of MUC1-DC-CTL Treatment in Stage IV Gastric Cancer.Beijing Doing Biomedical Co., Ltd. · NCT02602249
- PHASE1TERMINATEDVaccine Therapy in Treating Patients With Metastatic Breast CancerNational Cancer Institute (NCI) · NCT00071942
Wikidata facts
- Instance of
- protein
Show 2 more facts
- found in taxon
- Homo sapiens
- cell component
- vesicle
via Wikidata · CC0