MELTF
Sign in to saveAlso known as CD228, MAP97, MTF1, MTf, MFI2, melanotransferrin
Melanotransferrin is a protein that in humans is encoded by the MFI2 gene. MFI2 has also recently been designated CD228 (cluster of differentiation 228).
Gene data
MELTF- Name
- melanotransferrin
- Type
- protein-coding
- Aliases
- CD228, MAP97, MFI2, MTF1, MTf
The protein encoded by this gene is a cell-surface glycoprotein found on melanoma cells. The protein shares sequence similarity and iron-binding properties with members of the transferrin superfamily. The importance of the iron binding function has not yet been identified. This gene resides in the same region of chromosome 3 as members of the transferrin superfamily. Alternative splicing results in two transcript variants. [provided by RefSeq, Jul 2008].
via MyGene.info
Gene · Ensembl
melanotransferrin
- Symbol
- MELTF
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 3:196,980,590-197,029,874
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
Show 5 more facts
- HomoloGene ID
- 4335
- exact match
- identifiers.org/ncbigene/4241
- genomic end
- 197029835
- genomic start
- 196980590
- cytogenetic location
- 3q29
Sources (4)
via Wikidata · CC0
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3 sectionsContents
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Melanotransferrin is a protein that in humans is encoded by the MFI2 gene. MFI2 has also recently been designated CD228 (cluster of differentiation 228).
The protein encoded by this gene is a cell-surface glycoprotein found on melanoma cells. The protein shares sequence similarity and iron-binding properties with members of the transferrin superfamily. The importance of the iron binding function has not yet been identified. This gene resides in the same region of chromosome 3 as members of the transferrin superfamily. Alternative splicing results in two transcript variants. It is part of neural crest tissue, often present in melanotic neuroectodermal tumor of infancy.