CRIP2

Also known as CRIP, CRP2, ESP1, cysteine rich protein 2

Cysteine-rich protein 2 is a protein that in humans is encoded by the CRIP2 gene.

In the Vinony graph

Vinony's link graph records 3 inbound references to CRIP2, and connects out to PubMed, human chromosome 14 and Ensembl genome database project.

It is catalogued under the topic Genes on human chromosome 14.

Vinony links it to 7 Wikipedia language editions.

Gene data

CRIP2

Name: cysteine rich protein 2
Type: protein-coding
Position: 105,472,940–105,480,170 (+)
Aliases: CRIP, CRP2, ESP1
Ensembl: ENSG00000182809
RefSeq RNA: NM_001270837.2, NM_001270841.2, NM_001312.4, NR_073081.2, NR_073082.2
RefSeq protein: NP_001257766.1, NP_001257770.1, NP_001303.1

This gene encodes a putative transcription factor with two LIM zinc-binding domains. The encoded protein may participate in the differentiation of smooth muscle tissue. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012].

Gene Ontology

Molecular function

protein binding zinc ion binding

Cellular component

cell cortex

Pathways

VEGFA-VEGFR2 Signaling Pathway

via MyGene.info

Gene · Ensembl

cysteine rich protein 2

Symbol: CRIP2
Biotype: Protein coding
Organism: Homo sapiens
Location: 14:105,472,940-105,480,170
Strand: Forward (+)
Assembly: GRCh38

View on Ensembl →

via Ensembl · EMBL-EBI

Wikidata facts

Instance of: gene
Image: Protein CRIP2 PDB 2cu8.png

Show 8 more facts

HomoloGene ID: 135666
found in taxon: Homo sapiens
exact match: identifiers.org/ncbigene/1397
chromosome: human chromosome 14
genomic start: 105939299
genomic end: 105480162
cytogenetic location: 14q32.33
expressed in: left ventricle

Sources (4)

via Wikidata · CC0

~1 min read

Encyclopedic overview

3 sections

Contents

References
External links
Further reading

Cysteine-rich protein 2 is a protein that in humans is encoded by the CRIP2 gene.

CRIP2 and the closely related CRIP1 are cysteine-rich proteins containing two LIM domains. They are highly expressed during cardiovascular development and act to bridge serum response factor and GATA proteins and stimulate smooth muscle target genes.

Excerpted from Wikipedia’s “CRIP2” article, available under the CC BY-SA 4.0 licence.