CST2
Sign in to saveAlso known as cystatin SA
Cystatin-SA is a protein that in humans is encoded by the CST2 gene.
Gene data
CST2- Name
- cystatin SA
- Type
- protein-coding
The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins and the kininogens. The type 2 cystatin proteins are a class of cysteine proteinase inhibitors found in a variety of human fluids and secretions, where they appear to provide protective functions. The cystatin locus on chromosome 20 contains the majority of the type 2 cystatin genes and pseudogenes. This gene is located in the cystatin locus and encodes a secreted thiol protease inhibitor found at high levels in saliva, tears and seminal plasma. [provided by RefSeq, Jul 2008].
via MyGene.info
Gene · Ensembl
cystatin SA
- Symbol
- CST2
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 20:23,823,769-23,826,735
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
Show 4 more facts
- exact match
- identifiers.org/ncbigene/1470
- genomic end
- 23826729
- genomic start
- 23804406
- cytogenetic location
- 20p11.21
Sources (3)
via Wikidata · CC0
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Article
3 sectionsContents
- References
- External links
- Further reading
Cystatin-SA is a protein that in humans is encoded by the CST2 gene.
The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins and the kininogens. The type 2 cystatin proteins are a class of cysteine proteinase inhibitors found in a variety of human fluids and secretions, where they appear to provide protective functions. The cystatin locus on chromosome 20 contains the majority of the type 2 cystatin genes and pseudogenes. This gene is located in the cystatin locus and encodes a secreted thiol protease inhibitor found at high levels in saliva, tears and seminal plasma.