CHMP2A
Sign in to saveAlso known as BC-2, BC2, CHMP2, VPS2, VPS2A, charged multivesicular body protein 2A
Charged multivesicular body protein 2a is a protein that in humans is encoded by the CHMP2A gene. It is a reference gene.
Gene data
CHMP2A- Name
- charged multivesicular body protein 2A
- Type
- protein-coding
- Position
- 58,551,452–58,555,128 (−)
- Aliases
- BC-2, BC2, CHMP2, VPS2, VPS2A
- Ensembl
- ENSG00000130724
- RefSeq RNA
- NM_014453.4, NM_198426.3, XM_005258746.3, XM_005258747.4, XM_054320574.1
- RefSeq protein
- NP_055268.1, NP_940818.1, XP_005258803.1, XP_005258804.1, XP_054176549.1
CHMP2A belongs to the chromatin-modifying protein/charged multivesicular body protein (CHMP) family. These proteins are components of ESCRT-III (endosomal sorting complex required for transport III), a complex involved in degradation of surface receptor proteins and formation of endocytic multivesicular bodies (MVBs). Some CHMPs have both nuclear and cytoplasmic/vesicular distributions, and one such CHMP, CHMP1A (MIM 164010), is required for both MVB formation and regulation of cell cycle progression (Tsang et al., 2006 [PubMed 16730941]).[supplied by OMIM, Mar 2008].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
charged multivesicular body protein 2A
- Symbol
- CHMP2A
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 19:58,551,452-58,555,129
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
Show 5 more facts
- HomoloGene ID
- 6382
- exact match
- identifiers.org/ncbigene/27243
- genomic end
- 58555105
- genomic start
- 58551452
- cytogenetic location
- 19q13.43
Sources (4)
via Wikidata · CC0
~1 min read
Article
3 sectionsContents
- References
- Further reading
- External links
Charged multivesicular body protein 2a is a protein that in humans is encoded by the CHMP2A gene. It is a reference gene.
==References==