SH2B2
Sign in to saveAlso known as APS, SH2B adaptor protein 2
SH2B adapter protein 2 is a protein that in humans is encoded by the SH2B2 gene.
Gene data
SH2B2- Name
- SH2B adaptor protein 2
- Type
- protein-coding
- Aliases
- APS
The protein encoded by this gene is expressed in B lymphocytes and contains pleckstrin homology and src homology 2 (SH2) domains. In Burkitt's lymphoma cell lines, it is tyrosine-phosphorylated in response to B cell receptor stimulation. Because it binds Shc independent of stimulation and Grb2 after stimulation, it appears to play a role in signal transduction from the receptor to the Shc/Grb2 pathway. [provided by RefSeq, Jun 2009].
via MyGene.info
Gene · Ensembl
SH2B adaptor protein 2
- Symbol
- SH2B2
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 7:102,284,995-102,321,712
- Strand
- Forward (+)
- Assembly
- GRCh38
View on Ensembl →
via Ensembl · EMBL-EBI
Wikidata facts
- Image
- Protein SH2B2 PDB 1q2h.png
Show 5 more facts
- HomoloGene ID
- 10309
- exact match
- identifiers.org/ncbigene/10603
- genomic start
- 101928405
- genomic end
- 101962178
- cytogenetic location
- 7q22.1
Sources (3)
via Wikidata · CC0
~1 min read
Article
4 sectionsContents
- Function
- Interactions
- References
- Further reading
SH2B adapter protein 2 is a protein that in humans is encoded by the SH2B2 gene.
== Function ==
Connections
Q180686
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Ensembl genome database project
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protein
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Wikidata
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gene
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chromosome
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digital object identifier
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human genome
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Q229883
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base pair
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locus
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gene expression
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Online Mendelian Inheritance in Man
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Protein Data Bank
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Q22908627
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human chromosome 7
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Q905695
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Gene Ontology
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protein-protein interaction
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