SH2D1B
Sign in to saveAlso known as EAT2, SH2 domain containing 1B
SH2 domain-containing protein 1B is a protein that in humans is encoded by the SH2D1B gene.
In the Vinony graph
Within Vinony's link graph, SH2D1B is referenced by 4 other articles, and connects out to PubMed, human chromosome 1 and Ensembl genome database project.
It is catalogued under the topic Genes on human chromosome 1.
Its subject is documented across 5 Wikipedia language editions.
Gene data
SH2D1B- Name
- SH2 domain containing 1B
- Type
- protein-coding
- Position
- 162,395,164–162,412,138 (−)
- Aliases
- EAT2
- Ensembl
- ENSG00000198574
- RefSeq RNA
- NM_053282.5
- RefSeq protein
- NP_444512.2
By binding phosphotyrosines through its free SRC (MIM 190090) homology-2 (SH2) domain, EAT2 regulates signal transduction through receptors expressed on the surface of antigen-presenting cells (Morra et al., 2001 [PubMed 11689425]).[supplied by OMIM, Mar 2008].
Gene Ontology
Biological process
Molecular function
Cellular component
Pathways
via MyGene.info
Gene · Ensembl
SH2 domain containing 1B
- Symbol
- SH2D1B
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 1:162,395,164-162,412,138
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 8 more facts
- HomoloGene ID
- 8070
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/117157
- chromosome
- human chromosome 1
- genomic start
- 162395268
- genomic end
- 162381928
- cytogenetic location
- 1q23.3
- expressed in
- spleen
Sources (4)
via Wikidata · CC0
~1 min read
Encyclopedic overview
3 sectionsContents
- Interactions
- References
- Further reading
SH2 domain-containing protein 1B is a protein that in humans is encoded by the SH2D1B gene.
By binding phosphotyrosines through its free SRC (MIM 190090) homology-2 (SH2) domain, EAT2 regulates signal transduction through receptors expressed on the surface of antigen-presenting cells (Morra et al., 2001).[supplied by OMIM]
Excerpted from Wikipedia’s “SH2D1B” article, available under the CC BY-SA 4.0 licence.