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GeneQ18049282· pop 5· linked from 4 articles

Also known as EAT2, SH2 domain containing 1B

SH2 domain-containing protein 1B is a protein that in humans is encoded by the SH2D1B gene.

Gene data

SH2D1B
Name
SH2 domain containing 1B
Type
protein-coding
Aliases
EAT2

By binding phosphotyrosines through its free SRC (MIM 190090) homology-2 (SH2) domain, EAT2 regulates signal transduction through receptors expressed on the surface of antigen-presenting cells (Morra et al., 2001 [PubMed 11689425]).[supplied by OMIM, Mar 2008].

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Gene · Ensembl

SH2 domain containing 1B

Symbol
SH2D1B
Biotype
Protein coding
Organism
Homo sapiens
Location
1:162,395,164-162,412,138
Strand
Reverse (−)
Assembly
GRCh38
View on Ensembl →

via Ensembl · EMBL-EBI

Wikidata facts

Show 5 more facts
HomoloGene ID
8070
genomic start
162395268
genomic end
162381928
cytogenetic location
1q23.3
Sources (4)

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~1 min read

Article

3 sections
Contents
  • Interactions
  • References
  • Further reading

SH2 domain-containing protein 1B is a protein that in humans is encoded by the SH2D1B gene.

By binding phosphotyrosines through its free SRC (MIM 190090) homology-2 (SH2) domain, EAT2 regulates signal transduction through receptors expressed on the surface of antigen-presenting cells (Morra et al., 2001).[supplied by OMIM]

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