FCHSD2

Also known as NWK, SH3MD3, FCH and double SH3 domains 2, NWK1

FCH and double SH3 domains protein 2 is a protein that in humans is encoded by the FCHSD2 gene.

In the Vinony graph

Within Vinony's link graph, FCHSD2 is referenced by 3 other articles, and connects out to PubMed, human chromosome 11 and Ensembl genome database project.

It is catalogued under the topic Genes on human chromosome 11.

Its subject is documented across 6 Wikipedia language editions.

Gene data

FCHSD2

Name: FCH and double SH3 domains 2
Type: protein-coding
Position: 72,836,042–73,142,485 (−)
Aliases: NWK, NWK1, SH3MD3
Ensembl: ENSG00000137478
RefSeq RNA: NM_014824.3, XM_011545409.2, XM_011545410.3, XM_047427949.1, XM_047427950.1
RefSeq protein: NP_055639.2, XP_011543711.1, XP_011543712.1, XP_047283905.1, XP_047283906.1

Enables phosphatidylinositol-3,4,5-trisphosphate binding activity and phosphatidylinositol-3,4-bisphosphate binding activity. Involved in clathrin-dependent endocytosis and positive regulation of Arp2/3 complex-mediated actin nucleation. Located in plasma membrane. Colocalizes with clathrin-coated pit. [provided by Alliance of Genome Resources, Apr 2022]