RFC2
Sign in to saveAlso known as RFC40, replication factor C subunit 2
Replication factor C subunit 2 is a protein that in humans is encoded by the RFC2 gene.
Gene data
RFC2- Name
- replication factor C subunit 2
- Type
- protein-coding
- Aliases
- RFC40
This gene encodes a member of the activator 1 small subunits family. The elongation of primed DNA templates by DNA polymerase delta and epsilon requires the action of the accessory proteins, proliferating cell nuclear antigen (PCNA) and replication factor C (RFC). Replication factor C, also called activator 1, is a protein complex consisting of five distinct subunits. This gene encodes the 40 kD subunit, which has been shown to be responsible for binding ATP and may help promote cell survival. Disruption of this gene is associated with Williams syndrome. Alternatively spliced transcript variants encoding distinct isoforms have been described. A pseudogene of this gene has been defined on chromosome 2. [provided by RefSeq, Jul 2013].
via MyGene.info
Gene · Ensembl
replication factor C subunit 2
- Symbol
- RFC2
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 7:74,223,231-74,254,458
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
Show 5 more facts
- HomoloGene ID
- 6885
- exact match
- identifiers.org/ncbigene/5982
- genomic start
- 73645829
- genomic end
- 73668774
- cytogenetic location
- 7q11.23
Sources (4)
via Wikidata · CC0
~1 min read
Article
4 sectionsContents
- Function
- Interactions
- References
- Further reading
Replication factor C subunit 2 is a protein that in humans is encoded by the RFC2 gene.
== Function ==