CDH17
Sign in to saveAlso known as CDH16, HPT-1, HPT1, cadherin 17
Cadherin-17 is a protein that in humans is encoded by the CDH17 gene.
Gene data
CDH17- Name
- cadherin 17
- Type
- protein-coding
- Aliases
- CDH16, HPT-1, HPT1
This gene is a member of the cadherin superfamily, genes encoding calcium-dependent, membrane-associated glycoproteins. The encoded protein is cadherin-like, consisting of an extracellular region, containing 7 cadherin domains, and a transmembrane region but lacking the conserved cytoplasmic domain. The protein is a component of the gastrointestinal tract and pancreatic ducts, acting as an intestinal proton-dependent peptide transporter in the first step in oral absorption of many medically important peptide-based drugs. The protein may also play a role in the morphological organization of liver and intestine. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2009].
via MyGene.info
Gene · Ensembl
cadherin 17
- Symbol
- CDH17
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 8:94,124,381-94,217,303
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
Show 6 more facts
- HomoloGene ID
- 56859
- exact match
- identifiers.org/ncbigene/1015
- genomic end
- 95229531
- genomic start
- 94127162
- cytogenetic location
- 8q22.1
- Commons category
- Cadherin-17
Sources (4)
via Wikidata · CC0
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Cadherin-17 is a protein that in humans is encoded by the CDH17 gene.
This gene is a member of the cadherin superfamily, genes encoding calcium-dependent, membrane-associated glycoproteins. The encoded protein is cadherin-like, consisting of an extracellular region, containing 7 cadherin domains, and a transmembrane region but lacking the conserved cytoplasmic domain. The protein is a component of the gastrointestinal tract and pancreatic ducts, acting as an intestinal proton-dependent peptide transporter in the first step in oral absorption of many medically important peptide-based drugs. The protein may also play a role in the morphological organization of liver and intestine.