JAG2
Sign in to saveAlso known as HJ2, SER2, jagged 2, jagged canonical Notch ligand 2, LGMDR27
Jagged-2 is a protein that in humans is encoded by the JAG2 gene.
Gene data
JAG2- Name
- jagged canonical Notch ligand 2
- Type
- protein-coding
- Position
- 105,140,982–105,168,919 (−)
- Aliases
- HJ2, LGMDR27, SER2
- Ensembl
- ENSG00000184916
- RefSeq RNA
- NM_002226.5, NM_145159.3, XM_047431352.1, XM_047431353.1, XM_047431354.1
- RefSeq protein
- NP_002217.3, NP_660142.1, XP_047287308.1, XP_047287309.1, XP_047287310.1
The Notch signaling pathway is an intercellular signaling mechanism that is essential for proper embryonic development. Members of the Notch gene family encode transmembrane receptors that are critical for various cell fate decisions. The protein encoded by this gene is one of several ligands that activate Notch and related receptors. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
Gene Ontology
Biological process
Molecular function
Cellular component
Pathways
via MyGene.info
Gene · Ensembl
jagged canonical Notch ligand 2
- Symbol
- JAG2
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 14:105,140,982-105,168,919
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
Show 5 more facts
- HomoloGene ID
- 1677
- genomic start
- 105607318
- exact match
- identifiers.org/ncbigene/3714
- genomic end
- 105635161
- cytogenetic location
- 14q32.33
Sources (4)
via Wikidata · CC0
~1 min read
Article
4 sectionsContents
- Function
- Interactions
- References
- Further reading
Jagged-2 is a protein that in humans is encoded by the JAG2 gene.
== Function ==