JAG2

Also known as HJ2, SER2, jagged 2, jagged canonical Notch ligand 2, LGMDR27

Jagged-2 is a protein that in humans is encoded by the JAG2 gene.

Gene data

JAG2

Name: jagged canonical Notch ligand 2
Type: protein-coding
Position: 105,140,982–105,168,919 (−)
Aliases: HJ2, LGMDR27, SER2
Ensembl: ENSG00000184916
RefSeq RNA: NM_002226.5, NM_145159.3, XM_047431352.1, XM_047431353.1, XM_047431354.1
RefSeq protein: NP_002217.3, NP_660142.1, XP_047287308.1, XP_047287309.1, XP_047287310.1

The Notch signaling pathway is an intercellular signaling mechanism that is essential for proper embryonic development. Members of the Notch gene family encode transmembrane receptors that are critical for various cell fate decisions. The protein encoded by this gene is one of several ligands that activate Notch and related receptors. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].