DNM1
Sign in to saveAlso known as Dynamin-1, DNM, EIEE31, dynamin 1, DEE31
Dynamin-1 is a protein that in humans is encoded by the DNM1 gene.
Gene data
DNM1- Name
- dynamin 1
- Type
- protein-coding
- Aliases
- DEE31, DEE31A, DEE31B, DNM, EIEE31
This gene encodes a member of the dynamin subfamily of GTP-binding proteins. The encoded protein possesses unique mechanochemical properties used to tubulate and sever membranes, and is involved in clathrin-mediated endocytosis and other vesicular trafficking processes. Actin and other cytoskeletal proteins act as binding partners for the encoded protein, which can also self-assemble leading to stimulation of GTPase activity. More than sixty highly conserved copies of the 3' region of this gene are found elsewhere in the genome, particularly on chromosomes Y and 15. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008].
via MyGene.info
Gene · Ensembl
dynamin 1
- Symbol
- DNM1
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 9:128,191,655-128,255,254
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Image
- Protein DNM1 PDB 1dyn.png
Show 5 more facts
- HomoloGene ID
- 123905
- exact match
- identifiers.org/ncbigene/1759
- genomic end
- 131017527
- genomic start
- 130965658
- cytogenetic location
- 9q34.11
via Wikidata · CC0
~1 min read
Article
5 sectionsContents
- Function
- Role in disease
- Interactions
- References
- Further reading
Dynamin-1 is a protein that in humans is encoded by the DNM1 gene.
== Function ==