DNM1
Sign in to saveAlso known as Dynamin-1, DNM, EIEE31, dynamin 1, DEE31
Dynamin-1 is a protein that in humans is encoded by the DNM1 gene.
Gene data
DNM1- Name
- dynamin 1
- Type
- protein-coding
- Position
- 128,191,655–128,255,254 (+)
- Aliases
- DEE31, DEE31A, DEE31B, DNM, EIEE31
- Ensembl
- ENSG00000106976
- RefSeq RNA
- NM_001005336.3, NM_001288737.2, NM_001288738.2, NM_001288739.2, NM_001374269.1
- RefSeq protein
- NP_001005336.1, NP_001275666.1, NP_001275667.1, NP_001275668.1, NP_001361198.1
This gene encodes a member of the dynamin subfamily of GTP-binding proteins. The encoded protein possesses unique mechanochemical properties used to tubulate and sever membranes, and is involved in clathrin-mediated endocytosis and other vesicular trafficking processes. Actin and other cytoskeletal proteins act as binding partners for the encoded protein, which can also self-assemble leading to stimulation of GTPase activity. More than sixty highly conserved copies of the 3' region of this gene are found elsewhere in the genome, particularly on chromosomes Y and 15. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
dynamin 1
- Symbol
- DNM1
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 9:128,191,655-128,255,254
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
- Image
- Protein DNM1 PDB 1dyn.png
Show 8 more facts
- HomoloGene ID
- 123905
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/1759
- genomic end
- 131017527
- genomic start
- 130965658
- chromosome
- human chromosome 9
- cytogenetic location
- 9q34.11
- expressed in
- postcentral gyrus
via Wikidata · CC0
~1 min read
Encyclopedic overview
5 sectionsContents
- Function
- Role in disease
- Interactions
- References
- Further reading
Dynamin-1 is a protein that in humans is encoded by the DNM1 gene.
== Function ==
Excerpted from Wikipedia’s “DNM1” article, available under the CC BY-SA 4.0 licence.