MYH14
Sign in to saveAlso known as DFNA4, DFNA4A, MHC16, MYH17, NMHC II-C, NMHC-II-C, PNMHH, myosin
Myosin-14 is a protein that in humans is encoded by the MYH14 gene.
Gene data
MYH14- Name
- myosin heavy chain 14
- Type
- protein-coding
- Position
- 50,188,181–50,310,545 (+)
- Aliases
- DFNA4, DFNA4A, FP17425, MHC16, MYH17, NMHC II-C, NMHC-II-C, PNMHH, myosin
- Ensembl
- ENSG00000105357
- RefSeq RNA
- NM_001077186.2, NM_001145809.2, NM_024729.4
- RefSeq protein
- NP_001070654.1, NP_001139281.1, NP_079005.3
This gene encodes a member of the myosin superfamily. The protein represents a conventional non-muscle myosin; it should not be confused with the unconventional myosin-14 (MYO14). Myosins are actin-dependent motor proteins with diverse functions including regulation of cytokinesis, cell motility, and cell polarity. Mutations in this gene result in one form of autosomal dominant hearing impairment. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
myosin heavy chain 14
- Symbol
- MYH14
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 19:50,188,181-50,310,545
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 9 more facts
- HomoloGene ID
- 23480
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/79784
- genomic end
- 50310542
- genomic start
- 50691443
- chromosome
- human chromosome 19
- cytogenetic location
- 19q13.33
- genetic association
- nonsyndromic deafness
- expressed in
- tibialis anterior muscle
via Wikidata · CC0
~1 min read
Encyclopedic overview
3 sectionsContents
- References
- Further reading
- External links
Myosin-14 is a protein that in humans is encoded by the MYH14 gene.
This gene encodes a member of the myosin superfamily. Myosins are actin-dependent motor proteins with diverse functions, including regulation of cytokinesis, cell motility, and cell polarity. Mutations in this gene result in one form of autosomal dominant hearing impairment. Multiple transcript variants encoding different isoforms have been found for this gene.
Excerpted from Wikipedia’s “MYH14” article, available under the CC BY-SA 4.0 licence.