SPTBN5

Also known as BSPECV, HUBSPECV, HUSPECV, spectrin beta, non-erythrocytic 5

Spectrin, beta, non-erythrocytic 5 also known as SPTBN5 is a protein that in humans is encoded by the SPTBN5 gene. SPTBN5 belongs to the spectrin family of cytoskeletal proteins.

In the Vinony graph

Vinony's link graph records 272 inbound references to SPTBN5, and connects out to hair keratin, Q180686 and human chromosome 15.

It is catalogued under the topic Genes on human chromosome 15.

Vinony links it to 5 Wikipedia language editions.

Gene data

SPTBN5

Name: spectrin beta, non-erythrocytic 5
Type: protein-coding
Position: 41,848,146–41,894,053 (−)
Aliases: BSPECV, HUBSPECV, HUSPECV
Ensembl: ENSG00000137877
RefSeq RNA: NM_016642.4, XM_017022299.2, XM_017022302.2, XM_054378164.1, XM_054378165.1
RefSeq protein: NP_057726.4, XP_016877788.1, XP_016877791.1, XP_054234139.1, XP_054234140.1

Enables several functions, including cytoskeletal protein binding activity; dynein intermediate chain binding activity; and identical protein binding activity. Acts upstream of or within Golgi organization and lysosomal transport. Located in cytoplasm; photoreceptor connecting cilium; and photoreceptor disc membrane. [provided by Alliance of Genome Resources, Apr 2022]

Gene Ontology

Biological process

Golgi organization lysosomal transport actin cytoskeleton organization actin cytoskeleton organization

Molecular function

opsin binding actin binding cytoskeletal protein binding kinesin binding spectrin binding spectrin binding myosin tail binding dynactin binding

Cellular component

cytoplasm cytoplasm cytosol cytoskeleton microtubule associated complex plasma membrane spectrin membrane

Pathways

Developmental Biology Developmental Biology Signal Transduction ER to Golgi Anterograde Transport Membrane Trafficking L1CAM interactions L1CAM interactions NCAM signaling for neurite out-growth NCAM signaling for neurite out-growth Metabolism of proteins

via MyGene.info

Gene · Ensembl

spectrin beta, non-erythrocytic 5

Symbol: SPTBN5
Biotype: Protein coding
Organism: Homo sapiens
Location: 15:41,848,146-41,894,053
Strand: Reverse (−)
Assembly: GRCh38

View on Ensembl →

via Ensembl · EMBL-EBI

Wikidata facts

Show 5 more facts

HomoloGene ID: 41150
exact match: identifiers.org/ncbigene/51332
genomic end: 41894053
genomic start: 41848146
cytogenetic location: 15q15.1

Sources (3)

via Wikidata · CC0

~1 min read

Encyclopedic overview

3 sections

Contents

Structure and function
References
Further reading

Spectrin, beta, non-erythrocytic 5 also known as SPTBN5 is a protein that in humans is encoded by the SPTBN5 gene. SPTBN5 belongs to the spectrin family of cytoskeletal proteins.

== Structure and function ==

Excerpted from Wikipedia’s “SPTBN5” article, available under the CC BY-SA 4.0 licence.