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GeneQ18037852· pop 5· linked from 271 articles

KRT23

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Also known as CK23, HAIK1, K23, keratin 23

Keratin, type I cytoskeletal 23 is a protein that in humans is encoded by the KRT23 gene.

Gene data

KRT23
Name
keratin 23
Type
protein-coding
Position
40,922,696–40,937,646 (−)
Aliases
CK23, HAIK1, K23
Ensembl
ENSG00000108244
RefSeq RNA
NM_001282433.2, NM_015515.5, NM_173213.1, XM_005257200.6, XM_011524595.3
RefSeq protein
NP_001269362.1, NP_056330.3, XP_005257257.1, XP_011522897.1, XP_047291682.1

The protein encoded by this gene is a member of the keratin family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. The type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains. The type I cytokeratin genes are clustered in a region of chromosome 17q12-q21. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013].

Gene Ontology

Pathways

Estrogen signaling pathway - Homo sapiens (human)Staphylococcus aureus infection - Homo sapiens (human)Developmental BiologyKeratinizationFormation of the cornified envelopeDevelopmental Cell LineagesDevelopmental Cell Lineages of the Exocrine PancreasDevelopmental Lineage of Pancreatic Ductal Cells

via MyGene.info

Gene · Ensembl

keratin 23

Symbol
KRT23
Biotype
Protein coding
Organism
Homo sapiens
Location
17:40,922,696-40,937,646
Strand
Reverse (−)
Assembly
GRCh38
View on Ensembl →

via Ensembl · EMBL-EBI

Wikidata facts

Instance of
gene
Show 7 more facts
HomoloGene ID
9172
found in taxon
Homo sapiens
exact match
identifiers.org/ncbigene/25984
chromosome
human chromosome 17
genomic start
40922700
genomic end
40937646
cytogenetic location
17q21.2
Sources (4)

via Wikidata · CC0

~1 min read

Encyclopedic overview

2 sections
Contents
  • References
  • Further reading

Keratin, type I cytoskeletal 23 is a protein that in humans is encoded by the KRT23 gene.

The protein encoded by this gene is a member of the keratin family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratin and hair keratin. The type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains. The type I cytokeratin genes are clustered in a region of chromosome 17q12-q21.

Excerpted from Wikipedia’s “KRT23” article, available under the CC BY-SA 4.0 licence.

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via Wikidata sitelinks · CC0