SH3GL2
Sign in to saveAlso known as CNSA2, EEN-B1, SH3D2A, SH3P4, SH3 domain containing GRB2 like 2, endophilin A1
Endophilin-A1 is a protein that in humans is encoded by the SH3GL2 gene.
Gene data
SH3GL2- Name
- SH3 domain containing GRB2 like 2, endophilin A1
- Type
- protein-coding
- Position
- 17,579,060–17,797,129 (+)
- Aliases
- CNSA2, EEN-B1, SH3D2A, SH3P4
- Ensembl
- ENSG00000107295
- RefSeq RNA
- NM_003026.5, XM_011518005.4, XM_047423730.1, XM_054363551.1, XM_054363552.1
- RefSeq protein
- NP_003017.1, XP_011516307.1, XP_047279686.1, XP_054219526.1, XP_054219527.1
Enables identical protein binding activity. Involved in negative regulation of blood-brain barrier permeability; negative regulation of gene expression; and negative regulation of protein phosphorylation. Located in perinuclear region of cytoplasm. [provided by Alliance of Genome Resources, Apr 2022]
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
SH3 domain containing GRB2 like 2, endophilin A1
- Symbol
- SH3GL2
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 9:17,579,060-17,797,129
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
- Image
- Protein SH3GL2 PDB 1x03.png
Show 9 more facts
- HomoloGene ID
- 20652
- genetic association
- Parkinson's disease
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/6456
- genomic end
- 17797124
- genomic start
- 17579066
- chromosome
- human chromosome 9
- cytogenetic location
- 9p22.2
- expressed in
- orbitofrontal cortex
via Wikidata · CC0
~1 min read
Encyclopedic overview
3 sectionsContents
- Interactions
- References
- Further reading
Endophilin-A1 is a protein that in humans is encoded by the SH3GL2 gene.
==Interactions== SH3GL2 has been shown to interact with DNM1, Amphiphysin, ADAM9, SH3KBP1 and ADAM15.
Excerpted from Wikipedia’s “SH3GL2” article, available under the CC BY-SA 4.0 licence.