AP4E1
Sign in to saveAlso known as CPSQ4, SPG51, STUT1, adaptor related protein complex 4 epsilon 1 subunit, adaptor related protein complex 4 subunit epsilon 1
AP-4 complex subunit epsilon-1 is a protein that in humans is encoded by the AP4E1 gene.
Gene data
AP4E1- Name
- adaptor related protein complex 4 subunit epsilon 1
- Type
- protein-coding
- Aliases
- CPSQ4, SPG51, STUT1
This gene encodes a member of the adaptor complexes large subunit protein family. These proteins are components of the heterotetrameric adaptor protein complexes, which play important roles in the secretory and endocytic pathways by mediating vesicle formation and sorting of integral membrane proteins. The encoded protein is a large subunit of adaptor protein complex-4, which is associated with both clathrin- and nonclathrin-coated vesicles. Disruption of this gene may be associated with cerebral palsy. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Nov 2011].
via MyGene.info
Gene · Ensembl
adaptor related protein complex 4 subunit epsilon 1
- Symbol
- AP4E1
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 15:50,908,668-51,005,899
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
Show 5 more facts
- HomoloGene ID
- 22397
- exact match
- identifiers.org/ncbigene/23431
- genomic end
- 51005895
- genomic start
- 51200869
- cytogenetic location
- 15q21.2
via Wikidata · CC0
~1 min read
Article
5 sectionsContents
- Function
- Clinical relevance
- References
- External links
- Further reading
AP-4 complex subunit epsilon-1 is a protein that in humans is encoded by the AP4E1 gene.
== Function ==