POLE4
Sign in to saveAlso known as YHHQ1, p12, polymerase (DNA) epsilon 4, accessory subunit, DNA polymerase epsilon 4, accessory subunit
Polymerase (DNA-directed), epsilon 4, accessory subunit is a protein that in humans is encoded by the POLE4 gene.
Gene data
POLE4- Name
- DNA polymerase epsilon 4, accessory subunit
- Type
- protein-coding
- Position
- 74,958,643–74,970,128 (+)
- Aliases
- YHHQ1, p12
- Ensembl
- ENSG00000115350
- RefSeq RNA
- NM_019896.4
- RefSeq protein
- NP_063949.2
POLE4 is a histone-fold protein that interacts with other histone-fold proteins to bind DNA in a sequence-independent manner. These histone-fold protein dimers combine within larger enzymatic complexes for DNA transcription, replication, and packaging.[supplied by OMIM, Apr 2004].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
DNA polymerase epsilon 4, accessory subunit
- Symbol
- POLE4
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 2:74,958,636-75,147,205
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
Show 5 more facts
- HomoloGene ID
- 41339
- exact match
- identifiers.org/ncbigene/56655
- genomic end
- 75197255
- genomic start
- 74958643
- cytogenetic location
- 2p12
Sources (3)
via Wikidata · CC0
~1 min read
Article
3 sectionsContents
- Function
- References
- Further reading
Polymerase (DNA-directed), epsilon 4, accessory subunit is a protein that in humans is encoded by the POLE4 gene.
==Function==