DNA polymerase
Also known as deoxyribonucleic acid polymerase, deoxynucleate polymerase, DNA nucleotidyltransferase, deoxyribonucleic polymerase, deoxyribonucleate nucleotidyltransferase
Enzyme that synthesizes DNA from a nucleic acid template
Key facts
- Ec no
- 2.7.7.7
- Cas no
- 9012-90-2
- Intenz
- IntEnz view
- Brenda
- BRENDA entry
- Expasy
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- Kegg
- KEGG entry
- Metacyc
- metabolic pathway
- Priam
- profile
- Pdb structures
- RCSB PDB PDBe PDBsum
- Gene ontology
- AmiGO / QuickGO
- Pmc
- articles
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via Wikipedia infobox
~30 min read
Article
A DNA polymerase is a member of a family of enzymes that catalyze the synthesis of DNA molecules from nucleoside triphosphates, the molecular precursors of DNA. These enzymes are essential for DNA replication and usually work in groups to create two identical DNA duplexes from a single original DNA duplex. During this process, DNA polymerase "reads" the existing DNA strands to create two new strands that match the existing ones. These enzymes catalyze the chemical reaction
deoxynucleoside triphosphate + DNAn ⇌ pyrophosphate + DNAn+1.