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DNA polymerase

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DNA polymerase

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Also known as deoxyribonucleic acid polymerase, deoxynucleate polymerase, DNA nucleotidyltransferase, deoxyribonucleic polymerase, deoxyribonucleate nucleotidyltransferase

Enzyme that synthesizes DNA from a nucleic acid template

Key facts

Ec no
2.7.7.7
Cas no
9012-90-2
Intenz
IntEnz view
Brenda
BRENDA entry
Expasy
NiceZyme view
Kegg
KEGG entry
Metacyc
metabolic pathway
Priam
profile
Pdb structures
RCSB PDB PDBe PDBsum
Gene ontology
AmiGO / QuickGO
Pmc
articles
Pubmed
articles
Ncbi
proteins

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Wikidata facts

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DNA polymerase.png
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EC enzyme number
2.7.7.7
Commons category
DNA polymerases
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via Wikidata · CC0

~30 min read

Article

A DNA polymerase is a member of a family of enzymes that catalyze the synthesis of DNA molecules from nucleoside triphosphates, the molecular precursors of DNA. These enzymes are essential for DNA replication and usually work in groups to create two identical DNA duplexes from a single original DNA duplex. During this process, DNA polymerase "reads" the existing DNA strands to create two new strands that match the existing ones. These enzymes catalyze the chemical reaction

deoxynucleoside triphosphate + DNAn ⇌ pyrophosphate + DNAn+1.

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