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GeneQ18030754· pop 6· linked from 467 articles

Also known as p49, primase (DNA) subunit 1, DNA primase subunit 1

DNA primase small subunit is in humans is encoded by the PRIM1 gene and is part of the enzyme DNA polymerase alpha.

Gene data

PRIM1
Name
DNA primase subunit 1
Type
protein-coding
Aliases
PDIL, p49

The replication of DNA in eukaryotic cells is carried out by a complex chromosomal replication apparatus, in which DNA polymerase alpha and primase are two key enzymatic components. Primase, which is a heterodimer of a small subunit and a large subunit, synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication. The protein encoded by this gene is the small, 49 kDa primase subunit. [provided by RefSeq, Jul 2008].

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DNA primase subunit 1

Symbol
PRIM1
Biotype
Protein coding
Organism
Homo sapiens
Location
12:56,730,438-56,752,384
Strand
Reverse (−)
Assembly
GRCh38
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via Ensembl · EMBL-EBI

Wikidata facts

Show 5 more facts
HomoloGene ID
730
genomic end
56752374
genomic start
56731296
cytogenetic location
12q13.3
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DNA primase small subunit is in humans is encoded by the PRIM1 gene and is part of the enzyme DNA polymerase alpha.

The replication of DNA in eukaryotic cells is carried out by a complex chromosomal replication apparatus, in which DNA polymerase alpha and primase are two key enzymatic components. Primase, which is a heterodimer of a small subunit and a large subunit, synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication. The protein encoded by this gene is the small, 49 kDa primase subunit.

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