File:Alpha-Amanitin–RNA_polymerase_II_complex_1K83.png · Wikimedia Commons · See Wikimedia Commons
transferase
Sign in to saveAlso known as EC2, transferases
thumb|300px|right|RNA polymerase from [[Saccharomyces cerevisiae complexed with α-Amanitin (in red). Despite the use of the term "polymerase," RNA polymerases are classified as a form of nucleotidyl transferase.]]
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- EC 2. Transferases
- EC enzyme number
- 2.-.-.-
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~22 min read
Article
32 sectionsContents
- History
- Nomenclature
- Classification
- Role
- EC 2.1: single carbon transferases
- EC 2.2: aldehyde and ketone transferases
- EC 2.3: acyl transferases
- EC 2.4: glycosyl, hexosyl, and pentosyl transferases
- EC 2.5: alkyl and aryl transferases
- EC 2.6: nitrogenous transferases
- EC 2.7: phosphorus transferases
- EC 2.8: sulfur transferases
- EC 2.9: selenium transferases
- EC 2.10: metal transferases
- Role in histo-blood group
- Deficiencies
- SCOT deficiency
- CPT-II deficiency
- Galactosemia
- Choline acetyltransferase deficiencies
- Alzheimer's disease
- Amyotrophic lateral sclerosis (ALS or Lou Gehrig's disease)
- Huntington's disease
- Schizophrenia
- Sudden infant death syndrome (SIDS)
- Congenital myasthenic syndrome (CMS)
- Uses in biotechnology
- Terminal transferases
- Glutathione transferases
- Rubber transferases
- Membrane-associated transferases
- References
thumb|300px|right|RNA polymerase from [[Saccharomyces cerevisiae complexed with α-Amanitin (in red). Despite the use of the term "polymerase," RNA polymerases are classified as a form of nucleotidyl transferase.]]
In biochemistry, a transferase is any one of a class of enzymes that catalyse the transfer of specific functional groups (e.g. a methyl or glycosyl group) from one molecule (called the donor) to another (called the acceptor). They are involved in hundreds of different biochemical pathways throughout biology, and are integral to some of life's most important processes.