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کومافوس

Structure via PubChem · Public domain (PubChem)

EntityQ415896· pop 13· linked from 394 articles

کومافوس

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Also known as Coumafos, O-(3-chloro-4-methyl-2-oxo-2H-chromen-7-yl) O,O-diethyl thiophosphate, 3-Chloro-4-methyl-7-coumarinyl diethyl phosphorothioate, 3-Chloro-4-methyl-7-hydroxycoumarin diethyl thiophosphoric acid ester, 3-Chloro-7-diethoxyphosphinothioyloxy-4-methylcoumarin, 3-Chloro-7-hydroxy-4-methyl-coumarin O,O-diethyl phosphorothioate, O,O-Diethyl 3-chloro-4-methyl-7-umbelliferone thiophosphate, O,O-Diethyl O-(3-chloro-4-methyl-2-oxo-2H-1-benzopyran-7-yl)phosphorothioate

Coumaphos is a nonvolatile, fat-soluble phosphorothioate with ectoparasiticide properties: it kills insects and mites. It is well known by a variety of brand names as a dip or wash, used on farm and domestic animals to control ticks, mites, flies and fleas.

Chemical data

Formula
C14H16ClO5PS
Molecular weight
362.8 g/mol
IUPAC name
3-chloro-7-diethoxyphosphinothioyloxy-4-methylchromen-2-one
SMILES
CCOP(=S)(OCC)OC1=CC2=C(C=C1)C(=C(C(=O)O2)Cl)C
InChIKey
BXNANOICGRISHX-UHFFFAOYSA-N
XLogP
4.5
Polar surface area
86.1 Ų
H-bond donors
0
H-bond acceptors
6
Formal charge
0

via PubChem

Drug data · ChEMBL

Max clinical phase
Phase 2
Molecule type
Small molecule

via ChEMBL · EBI

Wikidata facts

Mass
362.014
Show 4 more facts
chemical formula
C₁₄H₁₆ClO₅PS
canonical SMILES
CCOP(=S)(OCC)OC1=CC2=C(C=C1)C(=C(C(=O)O2)Cl)C
Commons category
Coumaphos
Sources (3)

via Wikidata · CC0