CPA4

Name

carboxypeptidase A4

Type

protein-coding

Position

130,293,134–130,324,180 (+)

Aliases

CPA3

Ensembl

ENSG00000128510

RefSeq RNA

NM_001163446.2, NM_016352.4, XM_047420438.1, XM_054358328.1

RefSeq protein

NP_001156918.1, NP_057436.2, XP_047276394.1, XP_054214303.1

This gene is a member of the carboxypeptidase A/B subfamily, and it is located in a cluster with three other family members on chromosome 7. Carboxypeptidases are zinc-containing exopeptidases that catalyze the release of carboxy-terminal amino acids, and are synthesized as zymogens that are activated by proteolytic cleavage. This gene could be involved in the histone hyperacetylation pathway. It is imprinted and may be a strong candidate gene for prostate cancer aggressiveness. [provided by RefSeq, Jul 2008].