creatinine
Also known as Cr, CRE, CREA
Creatinine (; ) is a breakdown product of creatine phosphate from muscle and protein metabolism. It is released at a constant rate by the body (depending on muscle mass).
Chemical data
- Formula
- C4H7N3O
- Molecular weight
- 113.12 g/mol
- IUPAC name
- 2-amino-1-methylimidazol-4-ol
- SMILES
- CN1C=C(N=C1N)O
- InChIKey
- BTXYOFGSUFEOLA-UHFFFAOYSA-N
- XLogP
- -0.4
- Polar surface area
- 64.1 Ų
- H-bond donors
- 2
- H-bond acceptors
- 3
- Formal charge
- 0
via PubChem
Article
10 sectionsContents
- Biological relevance
- Antibacterial and potential immunosuppressive properties
- Diagnostic use
- Serum creatinine
- Urine creatinine
- Interpretation
- Chemistry
- See also
- References
- External links
Creatinine (; ) is a breakdown product of creatine phosphate from muscle and protein metabolism. It is released at a constant rate by the body (depending on muscle mass).
==Biological relevance== Serum creatinine (a blood measurement) is an important indicator of kidney function, because it is an easily measured byproduct of muscle metabolism that is excreted unchanged by the kidneys. Creatinine itself is produced via a biological system involving creatine, phosphocreatine (also known as creatine phosphate), and adenosine triphosphate (ATP, the body's immediate energy supply).