File:Joseph_le_crétin_-_Fonds_Trutat_-_MHNT.PHa.912.PR34_cropped.jpg · Wikimedia Commons · See Wikimedia Commons
Key facts
- Other names
- Endemic cretinism
- Specialty
- Endocrinology
- Symptoms
- Goiter , mental impairment , poor growth , infertility , hair loss
via Wikipedia infobox
Health references
- ICD-10
- E00.0 — Congenital iodine-deficiency syndrome, neurological type
Clinical Trials
26 registered- RECRUITINGComparison of Levothyroxine Formulations in the Treatment of Congenital HypothyroidismIRCCS Azienda Ospedaliero-Universitaria di Bologna · NCT06724224
- NOT_YET_RECRUITINGMetabolic Risk Assessment in Prepubertal Children With Congenital HypothyroidismBuzzi Children's Hospital · NCT07126353
- RECRUITINGRole of Next Generation Sequencing in the Etiological Diagnosis of Permanent Congenital Hypothyroidism With in Situ ThyroidIRCCS Azienda Ospedaliero-Universitaria di Bologna · NCT06728735
- COMPLETEDA Study of 99m Tc Pertechnetate Produced in High Energy Cyclotron in Patients With Thyroid Scan IndicationCentre de recherche du Centre hospitalier universitaire de Sherbrooke · NCT02307175
- ACTIVE_NOT_RECRUITINGIodine Impact on Thyroid Function and Psychomotor Development, Observational Study in the Portuguese Minho RegionUniversity of Minho · NCT04288531
- NACOMPLETEDClinical and Genetic Analysis in Congenital Hypothyroidism Due to Thyroid Dysgenesis.Assistance Publique - Hôpitaux de Paris · NCT01916018
~9 min read
Encyclopedic overview
Congenital hypothyroidism due to iodine deficiency (ICD-11), or congenital iodine deficiency syndrome (CIDS, ICD-10), is a medical condition present at birth marked by impaired physical and mental development, due to insufficient thyroid hormone production (hypothyroidism) caused by insufficient dietary iodine during pregnancy. Iodine deficiency is one cause of underactive thyroid function at birth, called congenital hypothyroidism. Consistent with the broader category of congenital hypothyroidism, this subtype also manifests as what was historically termed cretinism if left untreated.
Symptoms may include: goiter, poor length growth in infants, reduced adult stature, thickened skin, hair loss, enlarged tongue, a protruding abdomen, delayed bone maturation and puberty in children, mental deterioration, neurological impairment, impeded ovulation, and infertility in adults.
Excerpted from Wikipedia’s “cretinism” article, available under the CC BY-SA 4.0 licence.
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