CRISPR

Also known as clustered regularly interspaced short palindromic repeats

数十塩基対の短い反復配列を含み、原核生物における一種の獲得免疫系として働く座位

In the Vinony graph

Within Vinony's link graph, CRISPR is referenced by 611 other articles, and connects out to deoxyribonucleic acid, bacteriophage and RNA interference.

It sits within the topics 1987 in biotechnology, 2015 in biotechnology and Biological engineering.

Its subject is documented across 44 Wikipedia language editions.

Key facts

Nonhuman protein.Name: Cascade (CRISPR-associated complex for antiviral defense)
Nonhuman protein.image: 4QYZ.png
Nonhuman protein.caption: CRISPR Cascade protein (cyan) bound to CRISPR RNA (green) and phage DNA (red)
Nonhuman protein.Organism: Escherichia coli
Nonhuman protein.TaxID: 511145
Nonhuman protein.Symbol: CRISPR
Nonhuman protein.EntrezGene: 947229
Nonhuman protein.PDB: 4QYZ
Nonhuman protein.UniProt: P38036
Nonhuman protein.RefSeqProtein: NP_417241.1
Protein family.Symbol: CRISPR_assoc
Protein family.Name: CRISPR associated protein CasC/Cse3/Cas6 (Type I effector RNase)
Protein family.image: PDB 1wj9 EBI.jpg
Protein family.caption: Crystal structure of a crispr-associated protein from Thermus thermophilus
Protein family.Pfam: PF08798
Protein family.InterPro: IPR010179
Protein family.CDD: cd09727
Protein family.Pfam_clan: CL0362

via Wikipedia infobox

Research

67,864 papers

Genome modification by CRISPR/Cas9.The FEBS journal · 2014
CRISPR/Cas9 Immune System as a Tool for Genome Engineering.Archivum immunologiae et therapiae experimentalis · 2017
CRISPR-Based Gene Therapies: From Preclinical to Clinical Treatments.Cells · 2024
Advances in therapeutic CRISPR/Cas9 genome editing.Translational research : the journal of laboratory and clinical medicine · 2016
CRISPR/Cas System: Recent Advances and Future Prospects for Genome Editing.Trends in plant science · 2019

via PubMed

Wikidata facts

Subclass of: DNA sequence
Image: CAS 4qyz.png

Show 5 more facts

Commons category: CRISPR
derivative work: CRISPR-Cas method
location of discovery: University of Osaka
discoverer or inventor: Yoshizumi Ishino
time of discovery or invention: 1987-00-00

Sources (2)

via Wikidata · CC0

Article · 日本語

CRISPR (英: clustered regularly interspaced short palindromic repeat; クリスパー)は数十塩基対の短い反復配列を含み、原核生物における一種の獲得免疫系として働く座位である。配列決定された原核生物のうち真正細菌の4割と古細菌の9割に見出されており、プラスミドやファージといった外来の遺伝性因子に対する抵抗性に寄与している。

Abstract from DBpedia / Wikipedia · CC BY-SA