CRLF1

Name

cytokine receptor like factor 1

Type

protein-coding

Position

18,572,220–18,607,741 (−)

Aliases

CISS, CISS1, CLF, CLF-1, NR6, zcytor5

Ensembl

ENSG00000006016

RefSeq RNA

NM_004750.5

RefSeq protein

NP_004741.1

This gene encodes a member of the cytokine type I receptor family. The protein forms a secreted complex with cardiotrophin-like cytokine factor 1 and acts on cells expressing ciliary neurotrophic factor receptors. The complex can promote survival of neuronal cells. Mutations in this gene result in Crisponi syndrome and cold-induced sweating syndrome. [provided by RefSeq, Oct 2009].