CRYM
Sign in to saveAlso known as DFNA40, THBP, crystallin mu
Mu-crystallin homolog also known as NADP-regulated thyroid-hormone-binding protein (THBP) is a protein that in humans is encoded by the CRYM gene. Multiple alternatively spliced transcript variants have been found for this gene.
Gene data
CRYM- Name
- crystallin mu
- Type
- protein-coding
- Aliases
- DFNA40, THBP
Crystallins are separated into two classes: taxon-specific and ubiquitous. The former class is also called phylogenetically-restricted crystallins. The latter class constitutes the major proteins of vertebrate eye lens and maintains the transparency and refractive index of the lens. This gene encodes a taxon-specific crystallin protein that binds NADPH and has sequence similarity to bacterial ornithine cyclodeaminases. The encoded protein does not perform a structural role in lens tissue, and instead it binds thyroid hormone for possible regulatory or developmental roles. Mutations in this gene have been associated with autosomal dominant non-syndromic deafness. [provided by RefSeq, Sep 2014].
via MyGene.info
Gene · Ensembl
crystallin mu
- Symbol
- CRYM
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 16:21,238,297-21,303,083
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Image
- Protein CRYM PDB 2i99.png
Show 5 more facts
- HomoloGene ID
- 1424
- exact match
- identifiers.org/ncbigene/1428
- genomic start
- 21250195
- genomic end
- 21314404
- cytogenetic location
- 16p12.2
Sources (4)
via Wikidata · CC0
~2 min read
Article
4 sectionsContents
- Function
- References
- External links
- Further reading
Mu-crystallin homolog also known as NADP-regulated thyroid-hormone-binding protein (THBP) is a protein that in humans is encoded by the CRYM gene. Multiple alternatively spliced transcript variants have been found for this gene.
== Function ==