cycloserine
Also known as PA-94, (+)-4-Amino-3-isoxazolidinone, alpha-Cycloserine, Cicloserina, PA 94, D-(+)-Cycloserine, (R)-4-AMINO-isoxazolidin-3-one, (+)-Cycloserine
Cycloserine, sold under the brand name Seromycin, is an antibiotic, used to treat tuberculosis. Specifically it is used, along with other antituberculosis medications, for active drug resistant tuberculosis. It is given by mouth.
Key facts
- Drug.Watchedfields
- changed
- Drug.verifiedrevid
- 460111047
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- Cycloserine.svg
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- skin-invert-image
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- 150px
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- Cycloserine ball-and-stick model.png
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- Drug.tradename
- Seromycin
- Drug.DailyMedID
- Seromycin
- Drug.routes_of_administration
- Oral
- Drug.class
- Antibiotic; Alanine racemase inhibitor; D-Alanine–D-alanine ligase inhibitor; NMDA receptor partial agonist; GABA-T inhibitor
Article
15 sectionsContents
- Medical uses
- Tuberculosis
- Pharmacology
- Mechanism of action
- Chemistry
- Chemical properties
- Synthesis
- History
- Society and culture
- Economics
- Research
- Psychiatric disorders
- Possible hallucinogenic effects
- References
- Further reading
Cycloserine, sold under the brand name Seromycin, is an antibiotic, used to treat tuberculosis. Specifically it is used, along with other antituberculosis medications, for active drug resistant tuberculosis. It is given by mouth.
Common side effects include allergic reactions, seizures, sleepiness, unsteadiness, and numbness. It is not recommended in people who have kidney failure, epilepsy, depression, or are alcoholics. It is unclear if use during pregnancy is safe for the baby. Cycloserine is similar in structure to the amino acid D-alanine and works by interfering with the formation of the bacteria's cell wall.