cefazaflur
Sign in to saveCefazaflur (INN) is a first-generation cephalosporin antibiotic. == Synthesis == Cefazaflur stands out among this group of analogues because it lacks an arylamide C-7 side chain (see cephacetrile for another example). thumb|center|700px|Cefazaflur synthesis: Cefazaflur is synthesized by reaction of 3-(1-methyl-1H-tetrazol-5-ylthiomethylene)-7-amino-cephem-4-carboxylic acid (1) with trifluoromethylthioacetyl chloride (2).
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Cefazaflur (INN) is a first-generation cephalosporin antibiotic. == Synthesis == Cefazaflur stands out among this group of analogues because it lacks an arylamide C-7 side chain (see cephacetrile for another example). thumb|center|700px|Cefazaflur synthesis: Cefazaflur is synthesized by reaction of 3-(1-methyl-1H-tetrazol-5-ylthiomethylene)-7-amino-cephem-4-carboxylic acid (1) with trifluoromethylthioacetyl chloride (2).
== References ==
Excerpted from Wikipedia’s “cefazaflur” article, available under the CC BY-SA 4.0 licence.
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