cefazaflur
Sign in to saveCefazaflur (INN) is a first-generation cephalosporin antibiotic. == Synthesis == Cefazaflur stands out among this group of analogues because it lacks an arylamide C-7 side chain (see cephacetrile for another example). thumb|center|700px|Cefazaflur synthesis: Cefazaflur is synthesized by reaction of 3-(1-methyl-1H-tetrazol-5-ylthiomethylene)-7-amino-cephem-4-carboxylic acid (1) with trifluoromethylthioacetyl chloride (2).
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 470.011
Show 4 more facts
- chemical formula
- C₁₃H₁₃F₃N₆O₄S₃
- Commons category
- Cefazaflur
- canonical SMILES
- CN1C(=NN=N1)SCC2=C(N3C(C(C3=O)NC(=O)CSC(F)(F)F)SC2)C(=O)O
- isomeric SMILES
- CN1C(=NN=N1)SCC2=C(N3[C@@H]([C@@H](C3=O)NC(=O)CSC(F)(F)F)SC2)C(=O)O
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Encyclopedic overview
2 sectionsContents
- Synthesis
- References
Cefazaflur (INN) is a first-generation cephalosporin antibiotic. == Synthesis == Cefazaflur stands out among this group of analogues because it lacks an arylamide C-7 side chain (see cephacetrile for another example). thumb|center|700px|Cefazaflur synthesis: Cefazaflur is synthesized by reaction of 3-(1-methyl-1H-tetrazol-5-ylthiomethylene)-7-amino-cephem-4-carboxylic acid (1) with trifluoromethylthioacetyl chloride (2).
== References ==
Excerpted from Wikipedia’s “cefazaflur” article, available under the CC BY-SA 4.0 licence.
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