cephaloridine
Sign in to saveAlso known as 40602, Kefloridin, Cephalomycine, cefaloridine, (6R,7R)-8-oxo-3-(pyridin-1-ium-1-ylmethyl)- 7-[(2-thiophen-2-ylacetyl)amino]-5-thia-1- azabicyclo[4.2.0]oct-2-ene-2-carboxylate, Loridine, (6R,7R)-8-oxo-3-(pyridinium-1-ylmethyl)-7-[(2-thienylacetyl)amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate, N-(7-(2'-Thienylacetamidoceph-3-ylmethyl))-pyridinium-2-carboxylate
Cephaloridine (or cefaloridine) is a first-generation semisynthetic derivative of antibiotic cephalosporin C. It is a Beta lactam antibiotic, like penicillin. Its chemical structure contains cephems,carboxyl groups and a pyridinium ring.
Research
7,492 papers- CEPHALORIDINE.British medical journal · 1964
- Biochemical mechanisms of cephaloridine nephrotoxicity.Life sciences · 1988
- Cephaloridine.Annals of internal medicine · 1973
- Cephaloridine encephalopathy.British medical journal (Clinical research ed.) · 1981
- Cephaloridine (Loridine).The Medical letter on drugs and therapeutics · 1968
via PubMed
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 415.066048
- Has use
- medication
Show 7 more facts
- chemical formula
- C₁₉H₁₇N₃O₄S₂
- defined daily dose
- 3
- World Health Organisation international non-proprietary name
- cefaloridine
- canonical SMILES
- C1C(=C(N2C(S1)C(C2=O)NC(=O)CC3=CC=CS3)C(=O)[O-])C[N+]4=CC=CC=C4
- isomeric SMILES
- C1C(=C(N2[C@H](S1)[C@@H](C2=O)NC(=O)CC3=CC=CS3)C(=O)[O-])C[N+]4=CC=CC=C4
- subject has role
- bactericide
- Commons category
- Cefaloridine
via Wikidata · CC0
~11 min read
Encyclopedic overview
17 sectionsContents
- History
- Structure & reactivity
- Synthesis
- Clinical use of cephaloridine
- Kinetics
- Absorption
- Distribution
- Pregnancy
- Metabolism and excretion
- Pharmacokinetics
- Adverse effects
- Toxicity
- Metabolism
- Symptoms of kidney damage caused by cephaloridine
- Complications caused by cephaloridine
- Treatment of kidney damage caused by cephaloridine
- References
Cephaloridine (or cefaloridine) is a first-generation semisynthetic derivative of antibiotic cephalosporin C. It is a Beta lactam antibiotic, like penicillin. Its chemical structure contains cephems,carboxyl groups and a pyridinium ring.
Cephaloridine is mainly used in veterinary practice. It is unique among cephalosporins in that it exists as a zwitterion.
Excerpted from Wikipedia’s “cephaloridine” article, available under the CC BY-SA 4.0 licence.
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