Structure via PubChem · Public domain (PubChem)
cefpodoxime
Sign in to saveCefpodoxime is an oral, third-generation cephalosporin antibiotic available in various generic preparations. It is active against both Gram-positive and Gram-negative organisms with notable exceptions including Pseudomonas aeruginosa, Enterococcus, and Bacteroides fragilis. It is typically used to treat acute otitis media, pharyngitis, sinusitis, and gonorrhea. It also finds use as oral continuation therapy when intravenous cephalosporins (such as ceftriaxone) are no longer necessary for continued treatment.
Chemical data
- Formula
- C15H17N5O6S2
- Molecular weight
- 427.5 g/mol
- IUPAC name
- (6R,7R)-7-[[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-methoxyiminoacetyl]amino]-3-(methoxymethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
- SMILES
- COCC1=C(N2[C@@H]([C@@H](C2=O)NC(=O)/C(=N\OC)/C3=CSC(=N3)N)SC1)C(=O)O
- InChIKey
- WYUSVOMTXWRGEK-HBWVYFAYSA-N
- XLogP
- -1.4
- Polar surface area
- 210 Ų
- H-bond donors
- 3
- H-bond acceptors
- 11
- Formal charge
- 0
via PubChem
Wikidata facts
- Mass
- 427.062025
Show 6 more facts
- chemical formula
- C₁₅H₁₇N₅O₆S₂
- World Health Organisation international non-proprietary name
- cefpodoxime
- isomeric SMILES
- COCC1=C(N2[C@@H]([C@@H](C2=O)NC(=O)/C(=N\OC)/C3=CSC(=N3)N)SC1)C(=O)O
- canonical SMILES
- COCC1=C(N2C(C(C2=O)NC(=O)C(=NOC)C3=CSC(=N3)N)SC1)C(=O)O
- defined daily dose
- 0.4
- Commons category
- Cefpodoxime
Sources (6)
via Wikidata · CC0
~4 min read
Article
4 sectionsContents
- Spectrum of bacterial susceptibility and resistance
- Brand names
- References
- External links
{{Drugbox | Verifiedfields = changed | verifiedrevid = 414053518 | image = Cefpodoxime.svg | image_class = skin-invert-image | width = 200 | alt =
| tradename = Vantin, others | Drugs.com = | MedlinePlus = a698024 | pregnancy_AU = B1 | routes_of_administration = By mouth