Structure via PubChem · Public domain (PubChem)
daprodustat
Sign in to saveAlso known as GSK-1278863, GSK1278863
Daprodustat, sold under the brand name Duvroq among others, is a medication that is used for the treatment of anemia due to chronic kidney disease. It is a hypoxia-inducible factor prolyl hydroxylase inhibitor. It is taken by mouth.
In the Vinony graph
Within Vinony's link graph, daprodustat is referenced by 30 other articles, and connects out to erythropoietin, Iron supplement and medication.
Vinony files it under Acetic acids, Barbiturates and Cyclohexyl compounds.
Its subject is documented across 6 Wikipedia language editions.
Chemical data
- Formula
- C19H27N3O6
- Molecular weight
- 393.4 g/mol
- IUPAC name
- 2-[(1,3-dicyclohexyl-2,4,6-trioxo-1,3-diazinane-5-carbonyl)amino]acetic acid
- SMILES
- C1CCC(CC1)N2C(=O)C(C(=O)N(C2=O)C3CCCCC3)C(=O)NCC(=O)O
- InChIKey
- RUEYEZADQJCKGV-UHFFFAOYSA-N
- XLogP
- 2.5
- Polar surface area
- 124 Ų
- H-bond donors
- 2
- H-bond acceptors
- 6
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Approved
- Molecule type
- Small molecule
- First approval
- 2023
- Admin. routes
- oral
- Indications
- anemia (phenotype), peripheral vascular disease, injury, chronic kidney disease
via ChEMBL · EBI
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 393.189986
- Has use
- medication
Show 5 more facts
- medical condition treated
- anemia
- Commons category
- Daprodustat
- canonical SMILES
- C1CCC(CC1)N2C(=O)C(C(=O)N(C2=O)C3CCCCC3)C(=O)NCC(=O)O
- chemical formula
- C₁₉H₂₇N₃O₆
- legal status (medicine)
- boxed warning
via Wikidata · CC0
~3 min read
Encyclopedic overview
6 sectionsContents
- Medical uses
- Adverse effects
- History
- Society and culture
- Research
- References
Daprodustat, sold under the brand name Duvroq among others, is a medication that is used for the treatment of anemia due to chronic kidney disease. It is a hypoxia-inducible factor prolyl hydroxylase inhibitor. It is taken by mouth.
The most common side effects include high blood pressure, thrombotic vascular events, abdominal pain, dizziness, and allergic reactions.
Excerpted from Wikipedia’s “daprodustat” article, available under the CC BY-SA 4.0 licence.