DEGS2

Name

delta 4-desaturase, sphingolipid 2

Type

protein-coding

Position

100,143,957–100,159,645 (−)

Aliases

C14orf66, DES2, FADS8

Ensembl

ENSG00000168350

RefSeq RNA

NM_206918.3, XM_006720043.4, XM_054375428.1

RefSeq protein

NP_996801.2, XP_006720106.1, XP_054231403.1

This gene encodes a bifunctional enzyme that is involved in the biosynthesis of phytosphingolipids in human skin and in other phytosphingolipid-containing tissues. This enzyme can act as a sphingolipid delta(4)-desaturase, and also as a sphingolipid C4-hydroxylase. [provided by RefSeq, Oct 2008].