Structure via PubChem · Public domain (PubChem)
demegestone
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Demegestone, sold under the brand name Lutionex, is a progestin medication which was previously used to treat luteal insufficiency but is now no longer marketed. It is taken by mouth.
Chemical data
- Formula
- C21H28O2
- Molecular weight
- 312.4 g/mol
- IUPAC name
- (8S,13S,14S,17S)-17-acetyl-13,17-dimethyl-1,2,6,7,8,11,12,14,15,16-decahydrocyclopenta[a]phenanthren-3-one
- SMILES
- CC(=O)[C@]1(CC[C@@H]2[C@@]1(CCC3=C4CCC(=O)C=C4CC[C@@H]23)C)C
- InChIKey
- JWAHBTQSSMYISL-MHTWAQMVSA-N
- XLogP
- 2.8
- Polar surface area
- 34.1 Ų
- H-bond donors
- 0
- H-bond acceptors
- 2
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Phase 2
- Molecule type
- Small molecule
via ChEMBL · EBI
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 312.209
Show 4 more facts
- chemical formula
- C₂₁H₂₈O₂
- isomeric SMILES
- CC(=O)[C@]1(CC[C@@H]2[C@@]1(CCC3=C4CCC(=O)C=C4CC[C@@H]23)C)C
- canonical SMILES
- CC(=O)C1(CCC2C1(CCC3=C4CCC(=O)C=C4CCC23)C)C
- Commons category
- Demegestone
Sources (2)
via Wikidata · CC0
~4 min read
Encyclopedic overview
12 sectionsContents
- Medical uses
- Side effects
- Pharmacology
- Pharmacodynamics
- Pharmacokinetics
- Chemistry
- History
- Society and culture
- Generic names
- Brand names
- Availability
- References
Demegestone, sold under the brand name Lutionex, is a progestin medication which was previously used to treat luteal insufficiency but is now no longer marketed. It is taken by mouth.
Demegestone is a progestin, or a synthetic progestogen, and hence is an agonist of the progesterone receptor, the biological target of progestogens like progesterone. It has no androgenic activity.
Excerpted from Wikipedia’s “demegestone” article, available under the CC BY-SA 4.0 licence.
Available in 8 languages
via Wikidata sitelinks · CC0