canrenone
Sign in to saveCanrenone, sold under the brand names Contaren, Luvion, Phanurane, and Spiroletan, is a steroidal antimineralocorticoid of the spirolactone group related to spironolactone which is used as a diuretic in Europe, including in Italy and Belgium. It is also an important active metabolite of spironolactone, and partially accounts for its therapeutic effects.
Research
426 papers- Canrenone Restores Vasorelaxation Impaired by Marinobufagenin in Human Preeclampsia.International journal of molecular sciences · 2022
- Clinical Efficacy of Canrenone in Restoring Sinus Rhythm in Patients With Atrial Fibrillation-A Pilot, Randomized, Double-Blind Study.Journal of cardiovascular pharmacology and therapeutics · 2025
- Antimineralocorticoids.Renal physiology and biochemistry · 1991
- Relative Efficacy of Spironolactone, Eplerenone, and cAnRenone in patients with Chronic Heart failure (RESEARCH): a systematic review and network meta-analysis of randomized controlled trials.Heart failure reviews · 2020
- Aldosterone receptor blockers spironolactone and canrenone: two multivalent drugs.Expert opinion on pharmacotherapy · 2014
via PubMed
Wikidata facts
- Mass
- 340.204
Show 4 more facts
- chemical formula
- C₂₂H₂₈O₃
- canonical SMILES
- CC12CCC(=O)C=C1C=CC3C2CCC4(C3CCC45CCC(=O)O5)C
- isomeric SMILES
- C[C@]12CCC(=O)C=C1C=C[C@@H]3[C@@H]2CC[C@]4([C@H]3CC[C@@]45CCC(=O)O5)C
- Commons category
- Canrenone
Sources (2)
via Wikidata · CC0
~4 min read
Article
13 sectionsContents
- Medical uses
- Heart failure
- Pharmacology
- Pharmacodynamics
- Pharmacokinetics
- As a metabolite
- History
- Society and culture
- Generic names
- Brand names
- Availability
- See also
- References
Canrenone, sold under the brand names Contaren, Luvion, Phanurane, and Spiroletan, is a steroidal antimineralocorticoid of the spirolactone group related to spironolactone which is used as a diuretic in Europe, including in Italy and Belgium. It is also an important active metabolite of spironolactone, and partially accounts for its therapeutic effects.
==Medical uses== Canrenone has been found to be effective in the treatment of hirsutism in women.
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