Structure via PubChem · Public domain (PubChem)
stanozolol
Sign in to saveAlso known as Tevabolin, WIN-14833, Winstrol, Stromba
Stanozolol (abbrev. Stz), sold under many brand names, is a synthetic androgen and anabolic steroid (AAS) medication derived from dihydrotestosterone (DHT). It is used to treat hereditary angioedema. It was developed by American pharmaceutical company Sterling-Winthrop in 1962, and has been approved by the U.S. Food and Drug Administration for human use, though it is no longer marketed in the United States. It is also used in veterinary medicine. Stanozolol has mostly been discontinued, and remains available in only a few countries. It is given by mouth in humans or by injection into muscle in
Key facts
- Drug.ATC_prefix
- A14
- Drug.ATC_suffix
- AA02
- Drug.PubChem
- 25249
- Drug.Verifiedfields
- verified
- Drug.Watchedfields
- verified
- Drug.verifiedrevid
- 470470548
- Drug.image
- Stanozolol.svg
- Drug.image_class
- skin-invert-image
- Drug.width
- 250px
- Drug.imageL
- Estanozolol-3D.png
- Drug.image_classL
- bg-transparent
- Drug.widthL
- 125px
- Drug.imageR
- Estanozolol-3D-CPK.png
- Drug.image_classR
- bg-transparent
- Drug.widthR
- 125px
- Drug.IUPAC_name
- (1S,3aS,3bR,5aS,10aS,10bS,12aS)-1,10a,12a-trimethyl-1,2,3,3a,3b,4,5,5a,6,7,10,10a,10b,11,12,12a-hexadecahydrocyclopenta[5,6]naphtho[1,2-f]indazol-1-ol
- Drug.tradename
- Winstrol, Stromba, others
- Drug.pregnancy_category
- X
via Wikipedia infobox
Chemical data
- Formula
- C21H32N2O
- Molecular weight
- 328.5 g/mol
- IUPAC name
- (1S,2S,10S,13R,14S,17S,18S)-2,17,18-trimethyl-6,7-diazapentacyclo[11.7.0.02,10.04,8.014,18]icosa-4(8),5-dien-17-ol
- SMILES
- C[C@]12CC[C@H]3[C@H]([C@@H]1CC[C@]2(C)O)CC[C@@H]4[C@@]3(CC5=C(C4)NN=C5)C
- InChIKey
- LKAJKIOFIWVMDJ-IYRCEVNGSA-N
- XLogP
- 4.5
- Polar surface area
- 48.9 Ų
- H-bond donors
- 2
- H-bond acceptors
- 2
- Formal charge
- 0
via PubChem
Research
791 papers- Stanozolol as a novel therapeutic agent in dermatology.Journal of the American Academy of Dermatology · 1995
- Stanozolol-induced bland cholestasis.Gastroenterologia y hepatologia · 2014
- GnRHa/Stanozolol Combined Therapy Maintains Normal Bone Growth in Central Precocious Puberty.Frontiers in endocrinology · 2021
- [STANOZOLOL IN PEDIATRICS].La Semana medica · 1963
- Stanozolol-N-glucuronide metabolites in human urine samples as suitable targets in terms of routine anti-doping analysis.Drug testing and analysis · 2021
via PubMed
~14 min read
Encyclopedic overview
17 sectionsContents
- Medical uses
- Non-medical uses
- Side effects
- Pharmacology
- Pharmacodynamics
- Pharmacokinetics
- Chemistry
- Synthesis
- Detection in body fluids
- History
- Society and culture
- Generic names
- Brand names
- Legal status in the United States
- Doping in sports
- Research
- References
Stanozolol (abbrev. Stz), sold under many brand names, is a synthetic androgen and anabolic steroid (AAS) medication derived from dihydrotestosterone (DHT). It is used to treat hereditary angioedema. It was developed by American pharmaceutical company Sterling-Winthrop in 1962, and has been approved by the U.S. Food and Drug Administration for human use, though it is no longer marketed in the United States. It is also used in veterinary medicine. Stanozolol has mostly been discontinued, and remains available in only a few countries. It is given by mouth in humans or by injection into muscle in animals.
Unlike most AAS, stanozolol is not esterified and is sold as an aqueous suspension, or in oral tablet form. The drug has a high oral bioavailability, due to a C17α alkylation which allows the hormone to survive first-pass liver metabolism when ingested. It is because of this that stanozolol is also sold in tablet form.
Excerpted from Wikipedia’s “stanozolol” article, available under the CC BY-SA 4.0 licence.