difenoxin
Also known as difenoxin hydrochloride, MCN-JR-15,403-11, Motofen®, R-15403, diphenoxilic acid, 1-(3-cyano-3,3-diphenylpropyl)-4-phenylisonipecotic acid, diphenoxylic acid, Diphenoxilic acid
Difenoxin (Motofen, R-15403) is an opioid drug used, often in combination with atropine, to treat diarrhea. It is the principal metabolite of diphenoxylate.
Chemical data
- Formula
- C28H28N2O2
- Molecular weight
- 424.5 g/mol
- IUPAC name
- 1-(3-cyano-3,3-diphenylpropyl)-4-phenylpiperidine-4-carboxylic acid
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Approved
- Molecule type
- Small molecule
- First approval
- 1978
- Admin. routes
- oral
via ChEMBL · EBI
~4 min read
Article
5 sectionsContents
- Available forms
- Side effects
- Mechanism of action
- Legal status
- References
Difenoxin (Motofen, R-15403) is an opioid drug used, often in combination with atropine, to treat diarrhea. It is the principal metabolite of diphenoxylate.
It was first approved in the US in 1978 and in 1980 in the former West Germany.
Connections
Categories
4-PhenylpiperidinesAntidiarrhoealsChemical articles with multiple CAS registry numbersChemicals using indexlabelsDrugboxes which contain changes to verified fieldsDrugs with non-standard legal statusGamma-Amino acidsMultiple chemicals in Infobox drugMu-opioid receptor agonistsNitrilesSynthetic opioids