Structure via PubChem · Public domain (PubChem)
dimepheptanol
Sign in to saveDimepheptanol (INN; Amidol, Pangerin), also known as methadol or racemethadol, is a synthetic opioid analgesic related to methadone. It has similar effects to other opioids, including analgesia, sedation and euphoria, as well as side effects like itching, nausea and respiratory depression.
Chemical data
- Formula
- C21H29NO
- Molecular weight
- 311.5 g/mol
- IUPAC name
- 6-(dimethylamino)-4,4-diphenylheptan-3-ol
- SMILES
- CCC(C(CC(C)N(C)C)(C1=CC=CC=C1)C2=CC=CC=C2)O
- InChIKey
- QIRAYNIFEOXSPW-UHFFFAOYSA-N
- XLogP
- 3.7
- Polar surface area
- 23.5 Ų
- H-bond donors
- 1
- H-bond acceptors
- 2
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Phase 2
- Molecule type
- Small molecule
- Indications
- heroin dependence
via ChEMBL · EBI
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 311.225
Show 2 more facts
- chemical formula
- C₂₁H₂₉NO
- canonical SMILES
- CCC(C(CC(C)N(C)C)(C1=CC=CC=C1)C2=CC=CC=C2)O
Sources (2)
via Wikidata · CC0
~1 min read
Encyclopedic overview
2 sectionsContents
- See also
- References
Dimepheptanol (INN; Amidol, Pangerin), also known as methadol or racemethadol, is a synthetic opioid analgesic related to methadone. It has similar effects to other opioids, including analgesia, sedation and euphoria, as well as side effects like itching, nausea and respiratory depression.
Dimepheptanol is a mixture of two isomers, alphamethadol (α-methadol) and betamethadol (β-methadol). These are also available separately, and this drug has three separate entries in many national and international lists of illegal drugs, which refer to the racemic mixture dimepheptanol, and the two optical isomers. Each of these isomers is itself a mixture of two isomers, and so there are in fact four isomers of dimepheptanol in total; L-α-methadol, D-α-methadol, L-β-methadol and D-β-methadol.
Excerpted from Wikipedia’s “dimepheptanol” article, available under the CC BY-SA 4.0 licence.