File:Morphine.svg · Wikimedia Commons · See Wikimedia Commons
opioid
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Opioids are a class of drugs that derive from, or mimic, natural substances found in the opium poppy plant. Opioids work on opioid receptors in the brain and other organs to produce a variety of morphine-like effects, including pain relief.
Opioids are drugs derived from or chemically similar to substances found in the opium poppy plant that work by attaching to specific receptors in the brain and body. They are primarily used for pain relief, though they produce a range of morphine-like effects in the body.
AI-generated from the Wikipedia summary — may contain errors.
Key facts
- Drug class.Image
- Morphine2DCSDS.svg
- Drug class.ImageClass
- skin-invert-image
- Drug class.Caption
- Chemical structure of morphine, the prototypical opioid.
- Drug class.Use
- Pain relief
- Drug class.ATC_prefix
- N02A
- Drug class.Mode_of_action
- Opioid receptor
- Drug class.MeshID
- D000701
via Wikipedia infobox
Research
231,967 papers- Opioid metabolism.Mayo Clinic proceedings · 2009
- Opioid analgesics for nociceptive cancer pain: A comprehensive review.CA: a cancer journal for clinicians · 2024
- Toxicities of opioid analgesics: respiratory depression, histamine release, hemodynamic changes, hypersensitivity, serotonin toxicity.Archives of toxicology · 2021
- Opioid toxicity: histamine, hypersensitivity, and MRGPRX2.Archives of toxicology · 2023
- Opioid analgesics: Managing the predictable.Clinical medicine (London, England) · 2025
via PubMed
Wikidata facts
Show 2 more facts
- Commons category
- Opioids
- WordLift URL
- data.thenextweb.com/tnw/entity/opioid
Sources (3)
via Wikidata · CC0
~86 min read
Article
73 sectionsContents
- Terminology
- Medical uses
- Pain
- Acute pain
- Chronic non-cancer pain
- Other
- Cough
- Diarrhea
- Shortness of breath
- Restless legs syndrome
- Adverse effects
- Reinforcement disorders
- Tolerance
- Physical dependence
- Addiction
- Nausea and vomiting
- Drowsiness
- Itching
- Constipation
- Respiratory depression
- Increased pain sensitivity
- Other adverse effects
- Low sex hormone levels
- Disruption of work
- Increased accident-proneness
- Rare side effects
- Pregnancy
- Interactions
- With other depressant drugs
- Opioid antagonist
- Pharmacology
- Functional selectivity
- Opioid comparison
- Binding profiles
- Usage
- History
- Naturally occurring opioids
- Laudanum
- The opium trade
- Morphine
- Codeine
- <span class="anchor" id="Opioid#Semisynthetic and synthetic opioids"></span> Semi-synthetic and synthetic opioids
- Criminalization and medical use
- Society and culture
- Definition
- Efforts to reduce recreational use in the US
- Global shortages
- Recreational use
- Veterinary use
- Classification
- Endogenous opioids
- Opium alkaloids and derivatives
- Opium alkaloids
- Esters of morphine
- Ethers of morphine
- Semi-synthetic alkaloid derivatives
- Synthetic opioids
- Anilidopiperidines
- Benzimidazoles
- Phenylpiperidines
- Diphenylpropylamine derivatives
- Benzomorphan derivatives
- Oripavine derivatives
- Morphinan derivatives
- Others
- Allosteric modulators
- [[Opioid antagonist]]s
- Tables of opioids
- Table of morphinan opioids
- Table of non-morphinan opioids
- See also
- References
- External links
Opioids are a class of drugs that derive from, or mimic, natural substances found in the opium poppy plant. Opioids work on opioid receptors in the brain and other organs to produce a variety of morphine-like effects, including pain relief.
The terms "opioid" and "opiate" are sometimes used interchangeably, but the term "opioid" is used to designate all substances, both natural and synthetic, that bind to opioid receptors in the brain. Opiates are alkaloid compounds naturally found in the opium poppy plant Papaver somniferum.