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electroporation
EntityQ1142521· pop 28· linked from 222 articles

electroporation

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Also known as electropermeabilization

thumb|right|230px|Cuvettes for in-vitro electroporation. These are plastic with aluminium [[electrodes and a blue lid. They hold a maximum of 400 μL.]]

Research

19,242 papers

via PubMed

~17 min read

Encyclopedic overview

10 sections
Contents
  • Laboratory research
  • History
  • Medical applications
  • N-TIRE
  • Reversible electroporation
  • H-FIRE
  • Drug and gene delivery
  • Physical mechanism
  • Gene Electrotransfer
  • References

thumb|right|230px|Cuvettes for in-vitro electroporation. These are plastic with aluminium [[electrodes and a blue lid. They hold a maximum of 400 μL.]]

Electroporation, also known as electropermeabilization, is a microbiological and biotechnological technique in which an electric field is applied to cells to briefly increase the permeability of the cell membrane. The application of a high-voltage electric field induces a temporary destabilization of the lipid bilayer, resulting in the formation of nanoscale pores that permit the entry or exit of macromolecules.

Excerpted from Wikipedia’s “electroporation” article, available under the CC BY-SA 4.0 licence.

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