ENHO
Sign in to saveAlso known as C9orf165, UNQ470, energy homeostasis associated, Adropin, IPR034461
Adropin is a protein encoded by the energy homeostasis-associated gene ENHO in humans and is highly conserved across mammals.
Gene data
ENHO- Name
- energy homeostasis associated
- Type
- protein-coding
- Position
- 34,521,043–34,523,174 (−)
- Aliases
- C9orf165, UNQ470
- Ensembl
- ENSG00000168913
- RefSeq RNA
- NM_198573.3
- RefSeq protein
- NP_940975.2
Predicted to enable hormone activity. Predicted to be involved in positive regulation of Notch signaling pathway. Predicted to be located in extracellular region. Predicted to be active in plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]
Gene Ontology
Biological process
Molecular function
Cellular component
via MyGene.info
Gene · Ensembl
energy homeostasis associated
- Symbol
- ENHO
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 9:34,521,043-34,523,174
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
~6 min read
Encyclopedic overview
12 sectionsContents
- Structure
- Receptors and targets
- Function
- Metabolic
- Cardiovascular
- Central nervous system
- Circadian rhythm
- Gonads and sexual development
- Clinical significance
- Systemic sclerosis
- References
- Further reading
Adropin is a protein encoded by the energy homeostasis-associated gene ENHO in humans and is highly conserved across mammals.
The biological role of adropin was first described in mice by Andrew Butler's team. They identified it as a protein hormone (hepatokine) secreted from the liver, playing a role in obesity and energy homeostasis. The name "Adropin" is derived from the Latin words "aduro" (to set fire to) and "pinguis" (fat). Adropin is produced in various tissues, including the liver, brain, heart, and gastrointestinal tract.
Excerpted from Wikipedia’s “ENHO” article, available under the CC BY-SA 4.0 licence.