Structure via PubChem · Public domain (PubChem)
enocitabine
Sign in to saveEnocitabine (INN, marketed under the brand name Sunrabin) is a nucleoside analog used as chemotherapy.
In the Vinony graph
Vinony's link graph records 2 inbound references to enocitabine, and connects out to tiazofurin, medication and chemical formula.
It is catalogued under topics including Antineoplastic drugs, Chemical pages without DrugBank identifier and Drugs not assigned an ATC code.
Vinony links it to 4 Wikipedia language editions.
Chemical data
- Formula
- C31H55N3O6
- Molecular weight
- 565.8 g/mol
- IUPAC name
- N-[1-[(2R,3S,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-2-oxopyrimidin-4-yl]docosanamide
- SMILES
- CCCCCCCCCCCCCCCCCCCCCC(=O)NC1=NC(=O)N(C=C1)[C@H]2[C@H]([C@@H]([C@H](O2)CO)O)O
- InChIKey
- SAMRUMKYXPVKPA-VFKOLLTISA-N
- XLogP
- 9.2
- Polar surface area
- 132 Ų
- H-bond donors
- 4
- H-bond acceptors
- 6
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Phase 2
- Molecule type
- Small molecule
via ChEMBL · EBI
Research
179 papers- Phase 1 trial of gemtuzumab ozogamicin in combination with enocitabine and daunorubicin for elderly patients with relapsed or refractory acute myeloid leukemia: Japan Adult Leukemia Study Group (JALSG)-GML208 study.International journal of hematology · 2012
- [Cytarabine].Gan to kagaku ryoho. Cancer & chemotherapy · 1987
- [Cytidine].Nihon rinsho. Japanese journal of clinical medicine · 2015
- Clinical pharmacokinetics of cytarabine formulations.Clinical pharmacokinetics · 2002
- [Acute myeloid leukemia of the elderly: recent progresses in therapy].[Rinsho ketsueki] The Japanese journal of clinical hematology · 2018
via PubMed
Wikidata facts
- Mass
- 565.409
Show 4 more facts
- chemical formula
- C₃₁H₅₅N₃O₆
- Commons category
- Enocitabine
- isomeric SMILES
- CCCCCCCCCCCCCCCCCCCCCC(=O)NC1=NC(=O)N(C=C1)[C@H]2[C@H]([C@@H]([C@H](O2)CO)O)O
- canonical SMILES
- CCCCCCCCCCCCCCCCCCCCCC(=O)NC1=NC(=O)N(C=C1)C2C(C(C(O2)CO)O)O
Sources (2)
via Wikidata · CC0
~1 min read
Encyclopedic overview
1 sectionsContents
- References
Enocitabine (INN, marketed under the brand name Sunrabin) is a nucleoside analog used as chemotherapy.
Sunrabin contains the emulsifier HCO-60, which can cause allergic reactions.
Excerpted from Wikipedia’s “enocitabine” article, available under the CC BY-SA 4.0 licence.