Also known as epothilone
{| class="toccolours" border="1" style="float: right; clear: right; margin: 0 0 1em 1em; border-collapse: collapse;" ! | Epothilones |- | align="center" colspan="2" bgcolor="#ffffff"| 250px|Epothilones A (R = H) and B (R = Me) Epothilones A (R = H) and B (R = CH3) |- | Chemical formulae | A: C26H39NO6S B: C27H41NO6S |- | Molecular masses | A: 493.66 g/mol B: 507.68 g/mol |- | CAS numbers | A: 152044-53-6 B: 152044-54-7 |- | PubChem | A: 448799 B: 448013 |- | align="center" colspan="2" bgcolor="#ffffff"| 250px|Epothilones C (R = H) and D (R = Me) Epothilones C (R = H) and D (R = CH3) |- | Chemi
via PubMed
{| class="toccolours" border="1" style="float: right; clear: right; margin: 0 0 1em 1em; border-collapse: collapse;" ! | Epothilones |- | align="center" colspan="2" bgcolor="#ffffff"| 250px|Epothilones A (R = H) and B (R = Me) Epothilones A (R = H) and B (R = CH3) |- | Chemical formulae | A: C26H39NO6S B: C27H41NO6S |- | Molecular masses | A: 493.66 g/mol B: 507.68 g/mol |- | CAS numbers | A: 152044-53-6 B: 152044-54-7 |- | PubChem | A: 448799 B: 448013 |- | align="center" colspan="2" bgcolor="#ffffff"| 250px|Epothilones C (R = H) and D (R = Me) Epothilones C (R = H) and D (R = CH3) |- | Chemical formulae | C: C26H39NO5S D: C27H41NO5S |- | Molecular masses | C: 477.66 g/mol D: 491.68 g/mol |- | CAS numbers | C: 186692-73-9 D: 189453-10-9 |- | PubChem | C: 9891226 D: 447865 |- | align="center" colspan="2" bgcolor="#ffffff"| 250px|Epothilones E (R = H) and F (R = Me) Epothilones E (R = H) and F (R = CH3) |- | Chemical formulae | E: C26H39NO7S F: C27H41NO7S |- | Molecular masses | E: 509.66 g/mol F: 523.68 g/mol |- | CAS numbers | E: 201049-37-8 F: 208518-52-9 |- | PubChem | E: 9806341 F: 9914741 |- | | Disclaimer and references |}
Epothilones are a class of potential cancer drugs. Like taxanes, they prevent cancer cells from dividing by interfering with tubulin, but in early trials, epothilones have better efficacy and milder adverse effects than taxanes.
via Wikidata sitelinks · CC0
Discovered by embedding cosine similarity (sentence-transformers MiniLM, 384-dim).