ETFDH
Sign in to saveAlso known as electron-transferring-flavoprotein dehydrogenase, ETFQO, MADD, electron transfer flavoprotein dehydrogenase
Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial is an enzyme that in humans is encoded by the ETFDH gene. This gene encodes a component of the electron-transfer system in mitochondria and is essential for electron transfer from a number of mitochondrial flavin-containing dehydrogenases to the main respiratory chain.
Gene data
ETFDH- Name
- electron transfer flavoprotein dehydrogenase
- Type
- protein-coding
- Aliases
- ETFQO, MADD
This gene encodes a component of the electron-transfer system in mitochondria and is essential for electron transfer from a number of mitochondrial flavin-containing dehydrogenases to the main respiratory chain. Mutations in this gene are associated with glutaric acidemia. Alternatively spliced transcript variants that encode distinct isoforms have been observed. [provided by RefSeq, Aug 2013].
via MyGene.info
Gene · Ensembl
electron transfer flavoprotein dehydrogenase
- Symbol
- ETFDH
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 4:158,671,968-158,710,758
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
- Image
- Protein ETFDH PDB 2gmh.png
Show 8 more facts
- HomoloGene ID
- 3275
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/2110
- chromosome
- human chromosome 4
- genomic end
- 158710742
- genomic start
- 158671968
- cytogenetic location
- 4q32.1
- genetic association
- multiple acyl-CoA dehydrogenase deficiency
Sources (7)
via Wikidata · CC0
~3 min read
Encyclopedic overview
7 sectionsContents
- Function
- Structure
- Function
- Clinical Significance
- Interactions
- References
- Further reading
Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial is an enzyme that in humans is encoded by the ETFDH gene. This gene encodes a component of the electron-transfer system in mitochondria and is essential for electron transfer from a number of mitochondrial flavin-containing dehydrogenases to the main respiratory chain.
== Function ==
Excerpted from Wikipedia’s “ETFDH” article, available under the CC BY-SA 4.0 licence.