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GeneQ1161264· pop 6· linked from 6 articles

Also known as electron-transferring-flavoprotein dehydrogenase, ETFQO, MADD, electron transfer flavoprotein dehydrogenase

Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial is an enzyme that in humans is encoded by the ETFDH gene. This gene encodes a component of the electron-transfer system in mitochondria and is essential for electron transfer from a number of mitochondrial flavin-containing dehydrogenases to the main respiratory chain.

Gene data

ETFDH
Name
electron transfer flavoprotein dehydrogenase
Type
protein-coding
Aliases
ETFQO, MADD

This gene encodes a component of the electron-transfer system in mitochondria and is essential for electron transfer from a number of mitochondrial flavin-containing dehydrogenases to the main respiratory chain. Mutations in this gene are associated with glutaric acidemia. Alternatively spliced transcript variants that encode distinct isoforms have been observed. [provided by RefSeq, Aug 2013].

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Gene · Ensembl

electron transfer flavoprotein dehydrogenase

Symbol
ETFDH
Biotype
Protein coding
Organism
Homo sapiens
Location
4:158,671,968-158,710,758
Strand
Forward (+)
Assembly
GRCh38
View on Ensembl →

via Ensembl · EMBL-EBI

~3 min read

Encyclopedic overview

7 sections
Contents
  • Function
  • Structure
  • Function
  • Clinical Significance
  • Interactions
  • References
  • Further reading

Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial is an enzyme that in humans is encoded by the ETFDH gene. This gene encodes a component of the electron-transfer system in mitochondria and is essential for electron transfer from a number of mitochondrial flavin-containing dehydrogenases to the main respiratory chain.

== Function ==

Excerpted from Wikipedia’s “ETFDH” article, available under the CC BY-SA 4.0 licence.

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