Structure via PubChem · Public domain (PubChem)
etonitazene
Sign in to saveAlso known as EA-4941, CS-4640
Etonitazene, also known as EA-4941 or CS-4640, is a benzimidazole opioid, first reported in 1957, that has been shown to have approximately 1,000 to 1,500 times the potency of morphine in animals.
Chemical data
- Formula
- C22H28N4O3
- Molecular weight
- 396.5 g/mol
- IUPAC name
- 2-[2-[(4-ethoxyphenyl)methyl]-5-nitrobenzimidazol-1-yl]-N,N-diethylethanamine
- SMILES
- CCN(CC)CCN1C2=C(C=C(C=C2)[N+](=O)[O-])N=C1CC3=CC=C(C=C3)OCC
- InChIKey
- PXDBZSCGSQSKST-UHFFFAOYSA-N
- XLogP
- 4.3
- Polar surface area
- 76.1 Ų
- H-bond donors
- 0
- H-bond acceptors
- 5
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Phase 2
- Molecule type
- Small molecule
via ChEMBL · EBI
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 396.216141
Show 3 more facts
- chemical formula
- C₂₂H₂₈N₄O₃
- canonical SMILES
- CCN(CC)CCN1C2=C(C=C(C=C2)[N+](=O)[O-])N=C1CC3=CC=C(C=C3)OCC
- Commons category
- Etonitazene
Sources (2)
via Wikidata · CC0
~8 min read
Encyclopedic overview
7 sectionsContents
- Legal Status
- United Kingdom
- Analogs
- Illicit production
- Synthesis
- See also
- References
Etonitazene, also known as EA-4941 or CS-4640, is a benzimidazole opioid, first reported in 1957, that has been shown to have approximately 1,000 to 1,500 times the potency of morphine in animals.
Because it is characterized by a strong dependency potential and a tendency to produce profound respiratory depression, it is not used in humans. It is, however, useful in animal models for addiction studies, particularly those requiring the animals to drink or ingest the agent, because it is not as bitter as opiate salts like morphine sulfate.
Excerpted from Wikipedia’s “etonitazene” article, available under the CC BY-SA 4.0 licence.