FBXO4

Name

F-box protein 4

Type

protein-coding

Position

41,925,210–42,040,243 (+)

Aliases

FBX4

Ensembl

ENSG00000151876

RefSeq RNA

NM_001297437.2, NM_012176.3, NM_033484.3, XM_011514026.4, XM_011514027.3

RefSeq protein

NP_001284366.1, NP_036308.1, NP_277019.1, XP_011512328.1, XP_011512329.1

This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2014].

via MyGene.info

Gene · Ensembl

F-box protein 4

Symbol

FBXO4

Biotype

Protein coding

Organism

Homo sapiens

Location

5:41,925,210-42,040,243

Strand

Forward (+)

Assembly

GRCh38