FFAR4
Sign in to saveAlso known as BMIQ10, GPR120, GPR129, GT01, O3FAR1, PGR4, free fatty acid receptor 4
protein-coding gene in the species Homo sapiens
Gene data
FFAR4- Name
- free fatty acid receptor 4
- Type
- protein-coding
- Position
- 93,566,665–93,604,480 (+)
- Aliases
- BMIQ10, GPR120, GPR129, GT01, O3FAR1, OB10Q, PGR4
- Ensembl
- ENSG00000186188
- RefSeq RNA
- NM_001195755.2, NM_181745.4, XM_011539746.4, XM_054365713.1
- RefSeq protein
- NP_001182684.1, NP_859529.2, XP_011538048.1, XP_054221688.1
This gene encodes a G protein-coupled receptor (GPR) which belongs to the rhodopsin family of GPRs. The encoded protein functions as a receptor for free fatty acids, including omega-3, and participates in suppressing anti-inflammatory responses and insulin sensitizing. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2012].
Gene Ontology
Biological process
negative regulation of cytokine productionnegative regulation of cytokine productionG protein-coupled receptor signaling pathwayG protein-coupled receptor signaling pathwayadenylate cyclase-activating G protein-coupled receptor signaling pathwayadenylate cyclase-activating G protein-coupled receptor signaling pathwayphospholipase C-activating G protein-coupled receptor signaling pathwayphospholipase C-activating G protein-coupled receptor signaling pathway
Molecular function
Pathways
Signal TransductionSignal TransductionPeptide hormone metabolismSignaling by GPCRSignaling by GPCRClass A/1 (Rhodopsin-like receptors)Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)GPCR downstream signallingMetabolism of proteinsIncretin synthesis, secretion, and inactivation
via MyGene.info
Gene · Ensembl
free fatty acid receptor 4
- Symbol
- FFAR4
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 10:93,566,653-93,605,840
- Strand
- Forward (+)
- Assembly
- GRCh38
View on Ensembl →
via Ensembl · EMBL-EBI
Wikidata facts
Show 5 more facts
- HomoloGene ID
- 18769
- exact match
- identifiers.org/ncbigene/338557
- genomic start
- 95326422
- genomic end
- 95364237
- cytogenetic location
- 10q23.33
via Wikidata · CC0
Connections
adipocyte
Entity
amino acid
Entity
fatty acid
Entity
Q180686
Entity
macrophage
Entity
omega-3 fatty acid
Entity
endothelium
Entity
clinical trial
Entity
G protein-coupled recepteishon
Entity
low-density lipoprotein
Entity
tumor necrosis factor
Protein
human chromosome 10
Entity
Ensembl genome database project
Entity
isoform
Entity
taste receptor cell
Entity
pre-clinical development
Entity
FFAR1
Gene
G protein-coupled receptor, rhodopsin-like
Entity
FFAR2
Gene
disease
Entity