FSCN1

Name

fascin actin-bundling protein 1

Type

protein-coding

Position

5,592,806–5,606,656 (+)

Aliases

HSN, SNL, p55

Ensembl

ENSG00000075618

RefSeq RNA

NM_003088.4

RefSeq protein

NP_003079.1

This gene encodes a member of the fascin family of actin-binding proteins. Fascin proteins organize F-actin into parallel bundles, and are required for the formation of actin-based cellular protrusions. The encoded protein plays a critical role in cell migration, motility, adhesion and cellular interactions. Expression of this gene is known to be regulated by several microRNAs, and overexpression of this gene may play a role in the metastasis of multiple types of cancer by increasing cell motility. Expression of this gene is also a marker for Reed-Sternberg cells in Hodgkin's lymphoma. A pseudogene of this gene is located on the long arm of chromosome 15. [provided by RefSeq, Sep 2011].

via MyGene.info

Gene · Ensembl

fascin actin-bundling protein 1

Symbol

FSCN1

Biotype

Protein coding

Organism

Homo sapiens

Location

7:5,592,806-5,606,656

Strand

Forward (+)

Assembly

GRCh38

Wikidata facts

Instance of

gene

Image

Protein FSCN1 PDB 1dfc.png

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